Literature DB >> 30846049

Cognitive Functioning in Children with Down Syndrome: Current Knowledge and Future Directions.

Angela F Lukowski1, Helen M Milojevich2, Lauren Eales3.   

Abstract

Infants and children with Down syndrome (DS) can look forward toward bright futures, as individuals with DS are living healthier, more productive lives than ever due to medical advances, opportunities for early and continued intervention, and inclusive education. Despite these advances, infants and children with DS experience challenges in specific domains of cognitive functioning relative to their typically developing (TD) peers. Over the long term, individuals with DS are also more likely to develop Alzheimer's disease relative to the general population. Understanding cognitive functioning early in life may be important in charting cognitive decline over time. This chapter synthesizes the literature on cognitive functioning in infants and children with DS specific to general intelligence or IQ, language development, recall memory, and executive functioning, with additional focus on critical issues and future directions. These research findings provide important information for understanding cognitive competencies and intervention opportunities for children with DS and also serves to provide a foundation from which to plan longitudinal studies examining stability and change in cognitive functioning over time.
© 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cognition; Down syndrome; Executive functioning; Intelligence; Language; Memory

Mesh:

Year:  2019        PMID: 30846049     DOI: 10.1016/bs.acdb.2019.01.002

Source DB:  PubMed          Journal:  Adv Child Dev Behav        ISSN: 0065-2407


  10 in total

1.  Sleep problems and recall memory in children with Down syndrome and typically developing controls.

Authors:  Angela F Lukowski; Emily M Slonecker; Helen M Milojevich
Journal:  Res Dev Disabil       Date:  2019-11-16

2.  Language and executive functioning in young adults with Down syndrome.

Authors:  K Kristensen; K M Lorenz; X Zhou; B Piro-Gambetti; S L Hartley; S P Godar; S Diel; E Neubauer; R Y Litovsky
Journal:  J Intellect Disabil Res       Date:  2021-07-21

3.  Auditory-Perceptual Features of Speech in Children and Adults With Down Syndrome: A Speech Profile Analysis.

Authors:  Raymond D Kent; Julie Eichhorn; Erin M Wilson; Youmi Suk; Daniel M Bolt; Houri K Vorperian
Journal:  J Speech Lang Hear Res       Date:  2021-03-31       Impact factor: 2.297

4.  Plasma metabolome and cognitive skills in Down syndrome.

Authors:  Francesca Antonaros; Veronica Ghini; Francesca Pulina; Giuseppe Ramacieri; Elena Cicchini; Elisa Mannini; Anna Martelli; Agnese Feliciello; Silvia Lanfranchi; Sara Onnivello; Renzo Vianello; Chiara Locatelli; Guido Cocchi; Maria Chiara Pelleri; Lorenza Vitale; Pierluigi Strippoli; Claudio Luchinat; Paola Turano; Allison Piovesan; Maria Caracausi
Journal:  Sci Rep       Date:  2020-06-26       Impact factor: 4.379

Review 5.  Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome.

Authors:  Laszlo Pecze; Elisa B Randi; Csaba Szabo
Journal:  Mol Med       Date:  2020-11-09       Impact factor: 6.354

6.  Oral microbiome in down syndrome and its implications on oral health.

Authors:  Jesse R Willis; Susana Iraola-Guzmán; Ester Saus; Ewa Ksiezopolska; Luca Cozzuto; Luis A Bejarano; Nuria Andreu-Somavilla; Miriam Alloza-Trabado; Anna Puig-Sola; Andrea Blanco; Elisabetta Broglio; Carlo Carolis; Jochen Hecht; Julia Ponomarenko; Toni Gabaldón
Journal:  J Oral Microbiol       Date:  2020-12-30       Impact factor: 5.474

Review 7.  Development of Down Syndrome Research Over the Last Decades-What Healthcare and Education Professionals Need to Know.

Authors:  Karin Windsperger; Stefanie Hoehl
Journal:  Front Psychiatry       Date:  2021-12-14       Impact factor: 4.157

8.  A reassessment of Jackson's checklist and identification of two Down syndrome sub-phenotypes.

Authors:  Chiara Locatelli; Sara Onnivello; Caterina Gori; Giuseppe Ramacieri; Francesca Pulina; Chiara Marcolin; Renzo Vianello; Beatrice Vione; Maria Caracausi; Maria Chiara Pelleri; Lorenza Vitale; Gian Luca Pirazzoli; Guido Cocchi; Luigi Corvaglia; Pierluigi Strippoli; Francesca Antonaros; Allison Piovesan; Silvia Lanfranchi
Journal:  Sci Rep       Date:  2022-02-24       Impact factor: 4.379

Review 9.  A framework for the investigation of rare genetic disorders in neuropsychiatry.

Authors:  Stephan J Sanders; Mustafa Sahin; Joseph Hostyk; Audrey Thurm; Sebastien Jacquemont; Paul Avillach; Elise Douard; Christa L Martin; Meera E Modi; Andres Moreno-De-Luca; Armin Raznahan; Alan Anticevic; Ricardo Dolmetsch; Guoping Feng; Daniel H Geschwind; David C Glahn; David B Goldstein; David H Ledbetter; Jennifer G Mulle; Sergiu P Pasca; Rodney Samaco; Jonathan Sebat; Anne Pariser; Thomas Lehner; Raquel E Gur; Carrie E Bearden
Journal:  Nat Med       Date:  2019-09-23       Impact factor: 53.440

10.  Is the Age of Developmental Milestones a Predictor for Future Development in Down Syndrome?

Authors:  Chiara Locatelli; Sara Onnivello; Francesca Antonaros; Agnese Feliciello; Sonia Filoni; Sara Rossi; Francesca Pulina; Chiara Marcolin; Renzo Vianello; Enrico Toffalini; Giuseppe Ramacieri; Anna Martelli; Giulia Procaccini; Giacomo Sperti; Maria Caracausi; Maria Chiara Pelleri; Lorenza Vitale; Gian Luca Pirazzoli; Pierluigi Strippoli; Guido Cocchi; Allison Piovesan; Silvia Lanfranchi
Journal:  Brain Sci       Date:  2021-05-18
  10 in total

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