Yong-Cheng Ren1, Yu Liu2, Xi-Zhuo Sun2, Bing-Yuan Wang3, Yi Liu4, Hu Ni5, Yang Zhao3, Dechen Liu3, Xuejiao Liu3, Dongdong Zhang3, Feiyan Liu1, Cheng Cheng3, Leilei Liu3, Xu Chen3, Qionggui Zhou1, Ming Zhang1, Dongsheng Hu1. 1. 1Department of Preventive Medicine,Shenzhen University Health Sciences Center,3688 Nanhai Avenue,Nanshan District,Shenzhen,Guangdong 518060,People's Republic of China. 2. 2Study Team of Shenzhen's Sanming Project,The Affiliated Luohu Hospital of Shenzhen University Health Sciences Center,Shenzhen,Guangdong,People's Republic of China. 3. 3Department of Epidemiology and Health Statistics,College of Public Health,Zhengzhou University,Zhengzhou,Henan,People's Republic of China. 4. 4Publicity Department,Xin An Chinese Medicine Hospital,Luoyang,Henan,People's Republic of China. 5. 5Public Health Division,Xin An Chinese Medicine Hospital,Luoyang,Henan,People's Republic of China.
Abstract
OBJECTIVE: Limited information is available on the prevalence and effect of hypertriglyceridaemic-waist (HTGW) phenotype on the risk of type 2 diabetes mellitus (T2DM) in rural populations. DESIGN: In the present cross-sectional study, we investigated the prevalence of the HTGW phenotype and T2DM and the strength of their association among rural adults in China. SETTING: HTGW was defined as TAG >1·7 mmol/l and waist circumference (WC) ≥90 cm for males and ≥80 cm for females. Logistic regression analysis yielded adjusted odds ratios (aOR) relating risk of T2DM with HTGW.ParticipantsAdults (n 12 345) aged 22·83-92·58 years were recruited from July to August of 2013 and July to August of 2014 from a rural area of Henan Province in China. RESULTS: The prevalence of HTGW and T2DM was 23·71 % (males: 15·35 %; females: 28·88 %) and 11·79 % (males: 11·15 %; females: 12·18 %), respectively. After adjustment for sex, age, smoking, alcohol drinking, blood pressure, physical activity and diabetic family history, the risk of T2DM (aOR; 95 % CI) was increased with HTGW (v. normal TAG and WC: 3·23; CI 2·53, 4·13; males: 3·37; 2·30, 4·92; females: 3·41; 2·39, 4·85). The risk of T2DM with BMI≥28·0 kg/m2, simple enlarged WC and simple disorders of lipid metabolism showed an increasing tendency (aOR=1·31, 1·75 and 2·32). CONCLUSIONS: The prevalence of HTGW and T2DM has reached an alarming level among rural Chinese people, and HTGW is a significant risk factor for T2DM.
OBJECTIVE: Limited information is available on the prevalence and effect of hypertriglyceridaemic-waist (HTGW) phenotype on the risk of type 2 diabetes mellitus (T2DM) in rural populations. DESIGN: In the present cross-sectional study, we investigated the prevalence of the HTGW phenotype and T2DM and the strength of their association among rural adults in China. SETTING: HTGW was defined as TAG >1·7 mmol/l and waist circumference (WC) ≥90 cm for males and ≥80 cm for females. Logistic regression analysis yielded adjusted odds ratios (aOR) relating risk of T2DM with HTGW.ParticipantsAdults (n 12 345) aged 22·83-92·58 years were recruited from July to August of 2013 and July to August of 2014 from a rural area of Henan Province in China. RESULTS: The prevalence of HTGW and T2DM was 23·71 % (males: 15·35 %; females: 28·88 %) and 11·79 % (males: 11·15 %; females: 12·18 %), respectively. After adjustment for sex, age, smoking, alcohol drinking, blood pressure, physical activity and diabetic family history, the risk of T2DM (aOR; 95 % CI) was increased with HTGW (v. normal TAG and WC: 3·23; CI 2·53, 4·13; males: 3·37; 2·30, 4·92; females: 3·41; 2·39, 4·85). The risk of T2DM with BMI≥28·0 kg/m2, simple enlarged WC and simple disorders of lipid metabolism showed an increasing tendency (aOR=1·31, 1·75 and 2·32). CONCLUSIONS: The prevalence of HTGW and T2DM has reached an alarming level among rural Chinese people, and HTGW is a significant risk factor for T2DM.
Entities:
Keywords:
BMI; Hypertriglyceridaemic–waist phenotype; Public health; Type 2 diabetes mellitus; Waist-to-height ratio