Literature DB >> 30844721

CUEDC2: multifunctional roles in carcinogenesis.

Jun-Bo Xiao1, Ai-Min Leng2, Yan-Qiu Zhang1, Zhen Wen1, Jian He1, Guan-Nan Ye1.   

Abstract

The ubiquitously expressed multifunctional protein, CUEDC2 (CUE domain-containing 2), is involved in many physiological and pathological processes, including the cell cycle regulation and inflammation. Although it is known that CUEDC2 is expressed disparately in breast cancer, ovarian carcinoma, hepatocellular carcinoma, cholangiocarcinoma, glioma, lung adenocarcinoma, colon cancers, and is involved in the Warburg's effect, its role in oncogenesis remains to be further explored. In this review, we examine the expression of CUEDC2 in various tumors, and discuss several fundamental signaling pathways that are impacted by CUEDC2.

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Year:  2019        PMID: 30844721     DOI: 10.2741/4759

Source DB:  PubMed          Journal:  Front Biosci (Landmark Ed)        ISSN: 2768-6698


  4 in total

1.  CUEDC2 Drives β-Catenin Nuclear Translocation and Promotes Triple-Negative Breast Cancer Tumorigenesis.

Authors:  Shuyan Han; Huifeng Hao; Haibo Han; Dong Xue; Yanna Jiao; Yuntao Xie; Ye Xu; Longtao Huangfu; Jialei Fu; Shan Wang; Hong Sun; Pingping Li; Qun Zhou
Journal:  Cells       Date:  2022-09-29       Impact factor: 7.666

2.  Activation of PERK Contributes to Apoptosis and G2/M Arrest by Microtubule Disruptors in Human Colorectal Carcinoma Cells .

Authors:  Ming-Shun Wu; Chih-Chiang Chien; Ganbolor Jargalsaikhan; Noor Andryan Ilsan; Yen-Chou Chen
Journal:  Cancers (Basel)       Date:  2019-12-30       Impact factor: 6.639

3.  CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.

Authors:  Yue Cui; Yang Song; Shi Yan; Mengru Cao; Jian Huang; Dexin Jia; Yuechao Liu; Shuai Zhang; Weina Fan; Li Cai; Chunhong Li; Ying Xing
Journal:  Aging (Albany NY)       Date:  2020-10-25       Impact factor: 5.682

4.  Expression of CUE domain containing 2 protein in serous ovarian cancer tissue: predicting disease-free and overall survival of patients.

Authors:  Hu Lingyun; Li Ailing; Li Yali; You Yanqin; Ning Jing
Journal:  J Int Med Res       Date:  2020-09       Impact factor: 1.671

  4 in total

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