| Literature DB >> 30844393 |
Stephen G Waxman1, Sulayman D Dib-Hajj2.
Abstract
Sodium channel NaV1.7 is a major target in pain research, largely because of genetic validation. In this issue of Neuron, McDermott et al. (2019) now present a comprehensive assessment of congenital pain insensitivity due to NaV1.7 loss of function. This work and studies on NaV1.7 gain of function raise important questions about how channelopathies produce disease.Entities:
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Year: 2019 PMID： 30844393 DOI： 10.1016/j.neuron.2019.02.016
Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173