Organoiridium(III) Complexes as Luminescence Color Switching Probes for Selective Detection of Nerve Agent Simulant in Solution and Vapor Phase.

In this work, cationic organoiridium(III) complex based photoluminescent (PL) probes have been developed to selectively detect the chemical warfare nerve agent mimic, diethyl chlorophosphate(DCP) at nanomolar range by distinct bright green to orange-red luminescence color switching (on-off-on) in solution as well as in the vapor phase. Interference of other chemical warfare agents (CWAs) and their mimics was not observed either by PL spectroscopy or with the naked-eye in solution and gas phase. The detection was attained via a simultaneous nucleophilic attack of two -OH groups of the 4,7-dihydroxy-1,10-phenanthroline ligand with DCP by forming bulkier phosphotriester. The detailed reaction mechanism was established through extensive 1H NMR titration, 31P NMR, and ESI-MS analysis. Finally, a test paper strip and solid poly(ethylene oxide) (PEO) film with iridium(III) complex 1[PF6] were fabricated for the vapor-phase detection of DCP. The solution and vapor-phase detection properties of these luminescent Ir(III) complexes can offer a worthy approach into the design of new metal complex based PL switching probes for chemical warfare agents.