| Literature DB >> 30838223 |
Chun-Bing Chen1,2,3,4,5,6, Riichiro Abe7, Ren-You Pan1,2, Chuang-Wei Wang1,2, Shuen-Iu Hung8, Yi-Giien Tsai9,10,11, Wen-Hung Chung1,2,3,4,6,12.
Abstract
[This corrects the article DOI: 10.1155/2018/6431694.].Entities:
Year: 2019 PMID: 30838223 PMCID: PMC6374820 DOI: 10.1155/2019/2489429
Source DB: PubMed Journal: J Immunol Res ISSN: 2314-7156 Impact factor: 4.818
HLA association with various phenotypes of drug hypersensitivity in different populations.
| Associated drug | HLA allele | Hypersensitivity reactions | Ethnicity | Reference |
|---|---|---|---|---|
|
| ||||
| Carbamazepine |
| SJS/TEN | Han Chinese, Thai, Indian, Malaysian, Vietnam, Singapore, Hong Kong | [45, 82, 83, 226–230] |
|
| DRESS | Han Chinese, European, Spanish | [86, 87, 231] | |
|
| DRESS/SJS/TEN | Northern European, Japanese, Korean | [88–90] | |
|
| SJS/TEN | Han Chinese, Japanese, Korean, | [89, 232, 233] | |
|
| SJS/TEN | Japanese | [234] | |
| Oxcarbazepine |
| SJS/TEN | Han Chinese, Thai | [81, 84] |
| Phenytoin |
| SJS/TEN | Han Chinese, Thai | [81, 83] |
|
| SJS/TEN | Han Chinese, Japanese, Malaysian | [91] | |
|
| SJS/TEN | Thai | [235] | |
|
| DRESS | Thai | [235] | |
|
| DRESS/SJS/TEN | Malaysian | [236] | |
|
| DRESS/SJS/TEN | Han Chinese, Japanese, Malaysian | [91] | |
|
| SJS/TEN | Thai | [235] | |
| Lamotrigine |
| SJS/TEN | Han Chinese | [81, 85, 237] |
|
| SJS/TEN | European | [93, 238] | |
|
| SJS/TEN | Spanish | [231] | |
|
| SJS/TEN | Korean | [239] | |
|
| DRESS | Spanish | [231] | |
|
| ||||
|
|
| DRESS | Han Chinese, Thai, Japanese, Korean, European | [92–96] |
|
| ||||
|
| ||||
| Abacavir |
| HSS | European, African | [98, 99] |
| Nevirapine |
| DRESS | Australian | [240] |
|
| DRESS | Thai | [101] | |
|
| HSS | Sardinian, Japanese | [102, 241] | |
|
| DRESS/SJS/TEN | Malawian | [242] | |
|
| ||||
|
| ||||
| Beta-Lactam |
| Immediate type drug hypersensitivity | Chinese | [243] |
|
| Immediate type drug hypersensitivity | Spanish, Italian | [66] | |
| Cotrimoxazole |
| SJS/TEN | Thai | [244] |
| Dapsone |
| HSS | Han Chinese | [105] |
| Sulfamethoxazole |
| SJS/TEN | European | [93] |
| Sulfonamide |
| TEN | European | [245] |
|
| ||||
|
| ||||
| Aspirin |
| Urticaria/angioedema | Korean | [74] |
| Aspirin and other NSAIDs |
| Urticaria/angioedema and hypotension/laryngeal edema | Spanish | [246] |
| Aspirin and other NSAIDs |
| Chronic idiopathic urticaria | Italian | [75] |
| Oxicam NSAIDs |
| SJS/TEN | European | [93] |
|
| ||||
|
| ||||
| Methazolamide |
| SJS/TEN | Korean, Japanese | [108] |
DRESS: drug reaction with eosinophilia and systemic symptoms; HSS: hypersensitivity syndrome; MPE: maculopapular exanthema; NSAIDs: nonsteroidal anti-inflammatory drugs; SJS: Stevens-Johnson syndrome; TEN: toxic epidermal necrolysis.