Literature DB >> 30837718

Sildenafil/Viagra in the treatment of premature ejaculation.

Pramod Krishnappa1,2, Esau Fernandez-Pascual3, Joaquin Carballido3, Juan Ignacio Martinez-Salamanca3.   

Abstract

The arrival of Pfizer's blue pill Sildenafil in 1998 brought a great relief both to patient and physician signalling the start of a great era of medical therapy in sexual medicine. Since then the sexual medicine experts have been prescribing sildenafil in erectile dysfunction with acceptable minor adverse events. But the use of sildenafil in premature ejaculation (PE) is still debated. 2018 being the 20th anniversary of sildenafil, we have compiled interesting facts about the role of sildenafil in PE from various original articles, systematic reviews, meta-analyses, economic brochures and sexual medicine committee guidelines. The major issues in most of these studies were the heterogeneity in the definition of PE and estimating the exact ejaculatory latency time. This perspective article highlights the positive role of sildenafil in the management of PE (even without ED) with acceptable adverse events. Now that we have a standardised definition of PE from International Society of Sexual Medicine (ISSM) and a psychogenic component in PE definition, more randomised placebo-controlled studies are required to further establish its role.

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Year:  2019        PMID: 30837718     DOI: 10.1038/s41443-018-0099-2

Source DB:  PubMed          Journal:  Int J Impot Res        ISSN: 0955-9930            Impact factor:   2.896


  8 in total

Review 1.  Current and emerging treatment options for premature ejaculation.

Authors:  Murat Gul; Kadir Bocu; Ege Can Serefoglu
Journal:  Nat Rev Urol       Date:  2022-08-25       Impact factor: 16.430

2.  Novel Pyran-Linked Phthalazinone-Pyrazole Hybrids: Synthesis, Cytotoxicity Evaluation, Molecular Modeling, and Descriptor Studies.

Authors:  M Shaheer Malik; Basim H Asghar; Riyaz Syed; Reem I Alsantali; Moataz Morad; Hatem M Altass; Ziad Moussa; Ismail I Althagafi; Rabab S Jassas; Saleh A Ahmed
Journal:  Front Chem       Date:  2021-05-24       Impact factor: 5.221

Review 3.  Premature ejaculation - current concepts in the management: A narrative review.

Authors:  Arkiath Veettil Raveendran; Ankur Agarwal
Journal:  Int J Reprod Biomed       Date:  2021-01-25

4.  Central Retinal Artery Occlusion Associated with Sildenafil Overdose.

Authors:  Mojtaba Abrishami; Seyedeh Maryam Hosseini; Hamid Mohseni; Majid Razavi; Amir Ghaffarian Mashhadi Nejad; Mohammad Baghi Yazdi; Ghodsieh Zamani
Journal:  Case Rep Ophthalmol Med       Date:  2021-09-04

5.  Central Serous Chorioretinopathy Following Oral Use of Adulterated Honey Mixed with Tadalafil: A Case Report.

Authors:  Khalid S Asharari; Naif M Alali; Moustafa S Magliyah; Hassan A Al-Dhibi; Faisal A Almarek; Hani B AlBalawi
Journal:  Int Med Case Rep J       Date:  2021-11-15

6.  Case Report: Central retinal artery occlusion following sildenafil intake.

Authors:  Anis Mahmoud; Fatma Abid; Molka Khairallah; Fatma Sakji; Hassen Ibn Hadj Amor; Hala Attia; Sameh Mbarek; Riadh Messaoud
Journal:  F1000Res       Date:  2022-06-01

7.  Psychosis beas  a rare side effect of sildenafil: a case report.

Authors:  Mohammadreza Shalbafan; Maryam Orooji; Leila Kamalzadeh
Journal:  J Med Case Rep       Date:  2022-03-26

8.  Selective dorsal neurotomy in the treatment of premature ejaculation: A protocol for systematic review and meta-analysis.

Authors:  Guangsen Li; Degui Chang; Di'ang Chen; Peihai Zhang; Yaodong You; Xiaopeng Huang; Jian Cai
Journal:  Medicine (Baltimore)       Date:  2020-08-21       Impact factor: 1.817

  8 in total

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