| Literature DB >> 30836086 |
Xueyang Pan1, Michael B O'Connor2.
Abstract
Insect metamorphosis and mammalian puberty exhibit similar design principles, but the conservation of molecular components has not been documented. A new study demonstrates that the insect neuropeptide allatostatin A and its receptor AstAR1 activate a neuroendocrine signaling cascade that initiates metamorphosis, similar to the way in which their mammalian orthologs Kisspeptin and KISS1R induce puberty.Entities:
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Year: 2019 PMID： 30836086 DOI： 10.1016/j.cub.2019.01.040
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834