| Literature DB >> 30835483 |
Yu-Hao Ren1,2, Qun-Fang Liu1, Li Chen1,2, Shi-Jun He1, Jian-Ping Zuo1, Yao-Yue Fan1, Jian-Min Yue1,2.
Abstract
Urceoloids A (1) and B (2), two C19 steroids with a rearranged new carbon skeleton by featuring a very unique spiro[4.4]nona-3,6,8-triene system, and a biosynthetically related known steroid (3) were isolated from Urceola quintaretii. Their structures were completely established by a combined method. A plausible biosynthetic pathway for the new carbon skeleton represented by compounds 1 and 2 was proposed. Compounds 2 and 3 showed immunosuppressive activities.Entities:
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Year: 2019 PMID： 30835483 DOI： 10.1021/acs.orglett.9b00539
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005