Yi-Feng Qiu1, Yue-Jie Niu1, Xi Wei1, Bao-Qian Cao1, Xi-Cun Wang1, Zheng-Jun Quan1,2. 1. College of Chemistry and Chemical Engineering , Northwest Normal University , Lanzhou , Gansu 730070 , People's Republic of China. 2. Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials , Lanzhou , Gansu 730070 , People's Republic of China.
Abstract
A AgSCF3/Na2S2O8-promoted trifluoromethylthiolation/cascade cyclization of o-propargyl arylazides (or o-alkynyl benzylazides) triggered by a carbon-carbon triple bond is reported. This strategy provides the synthesis of valuable SCF3-substituted quinoline and isoquinoline systems via the construction of one C(sp2)-SCF3 bond and one C-N bond within one process.
A AgSCF3/n class="Chemical">Na2S2O8-promoted trifluoromethylthiolation/cascade cyclization of o-propargyl arylazides (or o-alkynyl benzylazides) triggered by a carbon-carbon triple bond is reported. This strategy provides the synthesis of valuable SCF3-substituted quinoline and isoquinoline systems via the construction of one C(sp2)-SCF3 bond and one C-N bond within one process.