Literature DB >> 30834065

A Rare Presentation of Hepatocellular Carcinoma in a Young Adult: A Case Report.

Erwa Eltayib Elmakki1.   

Abstract

Hepatocellular carcinoma is the most frequent type of liver malignancy. Most cases of hepatocellular carcinoma are secondary to either viral hepatitis (hepatitis B, C) or alcoholic cirrhosis. Liver cirrhosis due to any other causes is considered as a risk factor for development of hepatocellular carcinoma; however, hepatocellular carcinoma in a young patient with no cirrhosis or fibrosis is a relatively rare condition. The present case report describes a young 24-years-old male patient who presented with a two-month history of fever, right upper quadrant abdominal pain, and weight loss with no evidence of pre-existing liver disease, initially treated as liver abscess; however, a computed tomography (CT) showed numerous hepatic hypodensities with ring enhancement. Serum alpha-fetoprotein level was high (>1000 ng/L) and histopathological study confirmed the presence of primary hepatocellular carcinoma. The present case findings suggest that multifocal hepatocellular carcinoma can occur in a young patient with no apparent risk factor, and that the clinical presentation of hepatocellular carcinoma can be similar to liver abscess.

Entities:  

Keywords:  Chronic liver disease; Hepatocellular carcinoma; Liver abscess

Year:  2014        PMID: 30834065      PMCID: PMC6387664          DOI: 10.5001/omj.2014.19

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  10 in total

Review 1.  Hepatocellular carcinoma.

Authors:  Hashem B El-Serag
Journal:  N Engl J Med       Date:  2011-09-22       Impact factor: 91.245

2.  Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis: Is resection still the treatment of choice?

Authors:  Tito Livraghi; Franca Meloni; Michele Di Stasi; Emanuela Rolle; Luigi Solbiati; Carmine Tinelli; Sandro Rossi
Journal:  Hepatology       Date:  2008-01       Impact factor: 17.425

3.  Non-cirrhotic hepatocellular carcinoma in a young active duty male.

Authors:  David B Thomas; Andrew B Hall; Michael Michel
Journal:  Mil Med       Date:  2011-04       Impact factor: 1.437

4.  Severe hypercalcemia associated with hepatocellular carcinoma secreting intact parathyroid hormone: a case report.

Authors:  Yoko Abe; Hiroaki Makiyama; Yomo Fujita; Yasuhiro Tachibana; Go Kamada; Minoru Uebayashi
Journal:  Intern Med       Date:  2011-02-15       Impact factor: 1.271

5.  Fibrolamellar hepatocellular carcinoma: a case report with distinct radiological features.

Authors:  Ioannis Terzis; Afrodite Haritanti; Ipoliti Economou
Journal:  J Gastrointest Cancer       Date:  2010-03

Review 6.  Hepatocellular carcinoma in non-cirrhotic liver: a reappraisal.

Authors:  Franco Trevisani; Marta Frigerio; Valentina Santi; Alice Grignaschi; Mauro Bernardi
Journal:  Dig Liver Dis       Date:  2009-10-13       Impact factor: 4.088

7.  Severe hypercalcemia as an initial presenting manifestation of hepatocellular carcinoma.

Authors:  Michel William Ghobrial; John George; Sunitha Mannam; Samia R Henien
Journal:  Can J Gastroenterol       Date:  2002-09       Impact factor: 3.522

8.  Sorafenib in advanced hepatocellular carcinoma.

Authors:  Josep M Llovet; Sergio Ricci; Vincenzo Mazzaferro; Philip Hilgard; Edward Gane; Jean-Frédéric Blanc; Andre Cosme de Oliveira; Armando Santoro; Jean-Luc Raoul; Alejandro Forner; Myron Schwartz; Camillo Porta; Stefan Zeuzem; Luigi Bolondi; Tim F Greten; Peter R Galle; Jean-François Seitz; Ivan Borbath; Dieter Häussinger; Tom Giannaris; Minghua Shan; Marius Moscovici; Dimitris Voliotis; Jordi Bruix
Journal:  N Engl J Med       Date:  2008-07-24       Impact factor: 91.245

9.  Hepatocellular carcinoma with pyrexia: report of a case.

Authors:  T Hayashi; H Honda; K Kaneko; T Fukuya; Y Tateshi; T Ro; T Matsumata; E Adachi; K Masuda
Journal:  Radiat Med       Date:  1995 May-Jun

10.  [A case of hepatocellular carcinoma combined with liver abscess].

Authors:  Ju Ok Yeom; Seung Bae Yoon; Jae Gyung Kim; Jung Hwan Oh; Eun Jung Jeon; Jeong Jo Jeong; Sang Wook Choi; Seong Lee
Journal:  Korean J Gastroenterol       Date:  2009-06
  10 in total

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