Literature DB >> 30833098

An effective procedure for skin stiffness measurement to improve Paediatric Burn Care.

Julia Elrod1, Bettina Müller2, Christoph Mohr3, Martin Meuli4, Edoardo Mazza5, Clemens Schiestl6.   

Abstract

BACKGROUND: The objective evaluation of scar quality plays a crucial role in improving burn surgery and scar rehabilitation. Suction-based skin measurements were proposed as a method to objectively determine the mechanical properties of scars, yet their use is limited, in particular for paediatric burn care. A new device was developed which provides essential advantages for scar assessment. The aim of this study was to assess its reliability, intra- and interobserver variability.
METHODS: The new device, "Nimble", consists of a lightweight probe that measures the negative pressure needed to obtain a predefined tissue elevation, revealing information on the stiffness of the tissue. 29 former paediatric burn patients were included. Three observers measured the tissue stiffness of a predefined location on the scar and on healthy skin using the Nimble, and the established suction device, the Cutometer®. The reliability of both instruments in distinguishing between healthy skin and scar was assessed by means of the intraclass correlation coefficient.
RESULTS: The Nimble successfully differentiated between scar tissue and healthy skin in 92%, the Cutometer in 80% of the patients (p<0.05). Inter- and intraobserver variability of the Nimble (ICCs) were excellent. For the majority of the calculated ICC values the Nimble exceeded the Cutometer®.
CONCLUSION: The new device enables reliable and safe measurement of the stiffness of scars. Measurements are less susceptible to patient non-compliance and observer dependency. The Nimble might therefore constitute an easy to use tool for the systematic assessment of scars, thus supporting decision-making in paediatric burn care.
Copyright © 2019 Elsevier Ltd and ISBI. All rights reserved.

Entities:  

Keywords:  Burn; Cutometer; Nimble; Paediatric; Scar; Stiffness

Mesh:

Year:  2019        PMID: 30833098     DOI: 10.1016/j.burns.2019.02.004

Source DB:  PubMed          Journal:  Burns        ISSN: 0305-4179            Impact factor:   2.744


  4 in total

1.  Longitudinal monitoring and prediction of long-term outcome of scar stiffness on pediatric patients.

Authors:  Bettina Müller; Edoardo Mazza; Clemens Schiestl; Julia Elrod
Journal:  Burns Trauma       Date:  2021-09-30

2.  Towards the Development of a Device for Assessing the Pliability of Burn Scars.

Authors:  Francesco Dalle Mura; Lapo Governi; Rocco Furferi; Marta Cervo; Luca Puggelli
Journal:  Front Bioeng Biotechnol       Date:  2022-06-20

3.  Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds.

Authors:  Mateusz S Wietecha; Marco Pensalfini; Michael Cangkrama; Bettina Müller; Juyoung Jin; Jürgen Brinckmann; Edoardo Mazza; Sabine Werner
Journal:  Nat Commun       Date:  2020-05-25       Impact factor: 14.919

4.  Validation of the suction device Nimble for the assessment of skin fibrosis in systemic sclerosis.

Authors:  Bettina Müller; Lisa Ruby; Suzana Jordan; Marga B Rominger; Edoardo Mazza; Oliver Distler
Journal:  Arthritis Res Ther       Date:  2020-06-03       Impact factor: 5.156

  4 in total

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