Literature DB >> 30830596

Four-component green synthesis of benzochromene derivatives using nano-KF/clinoptilolite as basic catalyst: study of antioxidant activity.

Elham Ezzatzadeh1, Zinatossadat Hossaini2.   

Abstract

An efficient procedure for the synthesis of benzochromene derivatives employing 1-(6-hydroxy-2-isopropenyl-1-benzofuran-yl)-1-ethanone (euparin), aldehydes, alkyl bromides, dialkyl acetylenedicarboxylate and triphenylphosphine in the presence of KF/CP NPs as a heterogeneous base nano-catalyst in water at 80 °C is investigated. Also, the antioxidant activity of some synthesized compounds was studied. The workup of mixture of reaction is simple, and the products can be separated easily by filtration. KF/CP NPs showed a good improvement in the yield of the product and displayed significant reusable activity.

Entities:  

Keywords:  Aldehyde; Alkyl bromide; Euparin; Four-component reaction; Water

Year:  2019        PMID: 30830596     DOI: 10.1007/s11030-019-09935-6

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  18 in total

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Journal:  Comb Chem High Throughput Screen       Date:  2016       Impact factor: 1.339

5.  Multicomponent synthesis of 2-imidazolines.

Authors:  Robin S Bon; Bart van Vliet; Nanda E Sprenkels; Rob F Schmitz; Frans J J de Kanter; Christian V Stevens; Marcel Swart; F Matthias Bickelhaupt; Marinus B Groen; Romano V A Orru
Journal:  J Org Chem       Date:  2005-04-29       Impact factor: 4.354

6.  Ugi multicomponent reaction followed by an intramolecular nucleophilic substitution: convergent multicomponent synthesis of 1-sulfonyl 1,4-diazepan-5-ones and of their benzo-fused derivatives.

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Journal:  J Org Chem       Date:  2007-02-20       Impact factor: 4.354

7.  Novel one-pot three- and pseudo-five-component reactions: synthesis of functionalized benzo[g]- and dihydropyrano[2,3-g]chromene derivatives.

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8.  Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents.

Authors:  Koneni V Sashidhara; Jammikuntla N Rosaiah; Gitika Bhatia; J K Saxena
Journal:  Eur J Med Chem       Date:  2007-10-28       Impact factor: 6.514

9.  New MCRs: the first 4-component reaction leading to 2,4-disubstituted thiazoles.

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10.  KF/Clinoptilolite: an efficient promoter for the synthesis of thioethers.

Authors:  Sadegh Salmanpour; Mohammad A Khalilzadeh; Abolfazl Hosseini
Journal:  Comb Chem High Throughput Screen       Date:  2013-06-01       Impact factor: 1.339

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  3 in total

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2.  PANI-Fe3O4@ZnO nanocomposite as magnetically recoverable organometallic nanocatalyst promoted synthesis of new Azo chromene dyes and evaluation of their antioxidant and antimicrobial activities.

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3.  Synthesis and evaluation of the antioxidant activity of new spiro-1,2,4-triazine derivatives applying Ag/Fe3O4/CdO@MWCNT MNCs as efficient organometallic nanocatalysts.

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