Literature DB >> 3082980

Class-switching from mu to gamma 3 or gamma 2b production at pre-B cell stage.

H Sugiyama, T Maeda, S Akira, S Kishimoto.   

Abstract

An Abelson virus-transformed murine pre-B cell line class-switched from mu to gamma 3 or gamma 2b at the pre-B stage during culture. A class-switch was mediated by the deletion mechanism of the intervening CH genes on the active chromosome. This study showed for the first time that class-switching at the pre-B cell stage was not always confined to gamma 2b production.

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Year:  1986        PMID： 3082980

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  7 in total

1.  Infrequent utilization of the immunoglobulin heavy chain variable region(s) identical or closely related to that of MOPC315 myeloma protein in the functional V region formation in B-precursor cell lines.

Authors:  H Sugiyama; Y Minami; T Komori; N Sakato; S Kishimoto
Journal:  Immunology       Date:  1989-12       Impact factor: 7.397

2.  Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences.

Authors:  G A Daniels; M R Lieber
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205

3.  Analysis of the role of IL-21 in development of murine B cell progenitors in the bone marrow.

Authors:  Nathalie Simard; Danijela Konforte; Anne H Tran; Jessica Esufali; Warren J Leonard; Christopher J Paige
Journal:  J Immunol       Date:  2011-03-23       Impact factor: 5.422

4.  Nonhomologous recombination at sites within the mouse JH-C delta locus accompanies C mu deletion and switch to immunoglobulin D secretion.

Authors:  J D Owens; F D Finkelman; J D Mountz; J F Mushinski
Journal:  Mol Cell Biol       Date:  1991-11       Impact factor: 4.272

5.  Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors.

Authors:  Jin-Hwan Han; Shizuo Akira; Kathryn Calame; Bruce Beutler; Erik Selsing; Thereza Imanishi-Kari
Journal:  Immunity       Date:  2007-07-19       Impact factor: 31.745

6.  Selective use of the VHQ52 family in functional VH to DJH rearrangements in a B precursor cell line.

Authors:  H Sugiyama; T Maeda; Y Tani; S Miyake; Y Oka; T Komori; H Ogawa; T Soma; Y Minami; N Sakato
Journal:  J Exp Med       Date:  1987-08-01       Impact factor: 14.307

Review 7.  Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements.

Authors:  Audrey Dauba; Ahmed Amine Khamlichi
Journal:  Front Immunol       Date:  2021-09-14       Impact factor: 7.561
  7 in total

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