Literature DB >> 30827323

[EGFR-TKI ADR Management Chinese Expert Consensus].

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Abstract

ErbB receptor tyrosine kinase inhibitors (EGFR-TKI), gefitinib, erlotinib, icotinib and aftinib, which are approved as a frontline treatment for patients with non-small cell lung cancer (NSCLC) who have tumors harboring EGFR mutations in China. And osimertinib was approved in second line setting for patients with EGFRT 790M-positive NSCLC. Rash, paronychia, diarrhea, stomatitis, liver dysfunction and (interstitial lung disease, ILD) are frequently observed in patients treated with EGFR-TKI. Chinese Society of Lung Cancer, Chinese Anti-Cancer Association, organized Chinese experts to develop the Chinese expert consensus on EGFR-TKI adverse event (AE) management based on domestic diagnosis and treatment of ADR and also incorporating international updated theory and recommendations.
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Entities:  

Keywords:  Adverse drug reaction; Consensus; EGFR-TKI; Lung neoplasms

Mesh:

Substances:

Year:  2019        PMID: 30827323      PMCID: PMC6397940          DOI: 10.3779/j.issn.1009-3419.2019.02.01

Source DB:  PubMed          Journal:  Zhongguo Fei Ai Za Zhi        ISSN: 1009-3419


  6 in total

1.  Adverse Drug Reaction Discovery Using a Tumor-Biomarker Knowledge Graph.

Authors:  Meng Wang; Xinyu Ma; Jingwen Si; Hongjia Tang; Haofen Wang; Tunliang Li; Wen Ouyang; Liying Gong; Yongzhong Tang; Xi He; Wei Huang; Xing Liu
Journal:  Front Genet       Date:  2021-01-12       Impact factor: 4.599

2.  The Use of Traditional Chinese Medicine in Relieving EGFR-TKI-Associated Diarrhea Based on Network Pharmacology and Data Mining.

Authors:  Shuaihang Hu; Wenchao Dan; Jinlei Liu; Peng Ha; Tong Zhou; Xinyuan Guo; Wei Hou
Journal:  Evid Based Complement Alternat Med       Date:  2021-04-01       Impact factor: 2.629

3.  Severe stomatitis caused by osimertinib combined with gefitinib: A case report.

Authors:  Ya-Ning Zhu; Li Li; Peng Zhang; Yan Zuo; Yu Lei; Jun Bai; Lu Cao; Zhen-Jun Guo
Journal:  Clin Case Rep       Date:  2022-02-14

4.  [Recommendations from Experts in the Management of Adverse Reactions 
to ALK Inhibitors (2021 Version)].

Authors:  Ke Wang; Juan Li; Jianguo Sun; Li Li; Xi Zhang; Jianyong Zhang; Min Yu; Xianwei Ye; Ming Zhang; Yu Zhang; Wenxiu Yao; Meijuan Huang
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2021-10-21

5.  [Osimertinib Re-challenge for EGFR-mutant NSCLC after 
Osimertinib-induced Interstitial Lung Disease: A Case Report].

Authors:  Junjie Gu; Fan Bai; Lan Song; Yingyi Wang
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2021-11-20

6.  Fasudil Increased the Sensitivity to Gefitinib in NSCLC by Decreasing Intracellular Lipid Accumulation.

Authors:  Tingting Liao; Jingjing Deng; Wenjuan Chen; Juanjuan Xu; Guanghai Yang; Mei Zhou; Zhilei Lv; Sufei Wang; Siwei Song; Xueyun Tan; Zhengrong Yin; Yumei Li; Yang Jin
Journal:  Cancers (Basel)       Date:  2022-09-27       Impact factor: 6.575

  6 in total

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