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Literature DB >> 30826776

Could coenzyme Q10 be the treatment for Dupuytren's disease?

Abstract

A patient with Dupuytren's disease noted progressive disappearance of the contractures of both hands over a 3-year period while taking coenzyme Q10 daily for an unrelated condition. The function and appearance of his hands were restored to almost normal. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities: Disease Species

Keywords: drugs: musculoskeletal and joint diseases; medical management; orthopaedics

Mesh：

Substances：

Year: 2019 PMID： 30826776 PMCID： PMC6398680 DOI： 10.1136/bcr-2018-226419

Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X

12 in total

1. Dupuytren's contracture; a new concept of the pathogenesis correlated with surgical management.

Authors: J V LUCK
Journal: J Bone Joint Surg Am Date: 1959-06 Impact factor: 5.284

2. Safety and efficacy of coenzyme Q10 supplementation in early chronic Peyronie's disease: a double-blind, placebo-controlled randomized study.

Authors: M R Safarinejad
Journal: Int J Impot Res Date: 2010-08-19 Impact factor: 2.896

3. PEYRONIE'S DISEASE: A REVIEW OF ETIOLOGY, DIAGNOSIS, AND MANAGEMENT.

Authors: Aylin N Bilgutay; Alexander W Pastuszak
Journal: Curr Sex Health Rep Date: 2015-06-01

Review 4. Alternative and Adjunctive Treatments for Dupuytren Disease.

Authors: Paul M N Werker; Ilse Degreef
Journal: Hand Clin Date: 2018-06-08 Impact factor: 1.907

5. Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target.

Authors: Liaquat S Verjee; Jennifer S N Verhoekx; James K K Chan; Thomas Krausgruber; Vicky Nicolaidou; David Izadi; Dominique Davidson; Marc Feldmann; Kim S Midwood; Jagdeep Nanchahal
Journal: Proc Natl Acad Sci U S A Date: 2013-02-19 Impact factor: 11.205

Review 6. Treatment of Dupuytren's contracture: a systematic review.

Authors: E Soreide; M H Murad; J M Denbeigh; E A Lewallen; A Dudakovic; L Nordsletten; A J van Wijnen; S Kakar
Journal: Bone Joint J Date: 2018-09 Impact factor: 5.082

7. Rationale of combination therapy with antioxidants in medical management of Peyronie's disease: results of clinical application.

Authors: Gianni Paulis; Andrea Paulis; Gennaro Romano; Davide Barletta; Andrea Fabiani
Journal: Res Rep Urol Date: 2017-07-20

Review 8. Recent Pathophysiological Aspects of Peyronie's Disease: Role of Free Radicals, Rationale, and Therapeutic Implications for Antioxidant Treatment-Literature Review.

Authors: Gianni Paulis; Gennaro Romano; Luca Paulis; Davide Barletta
Journal: Adv Urol Date: 2017-07-04

9. Anti-Tumour Necrosis Factor Therapy for Dupuytren's Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial.

Authors: Jagdeep Nanchahal; Catherine Ball; Dominique Davidson; Lynn Williams; William Sones; Fiona E McCann; Marisa Cabrita; Jennifer Swettenham; Neil J Cahoon; Bethan Copsey; E Anne Francis; Peter C Taylor; Joanna Black; Vicki S Barber; Susan Dutton; Marc Feldmann; Sarah E Lamb
Journal: EBioMedicine Date: 2018-07-06 Impact factor: 8.143

Review 10. Coenzyme Q₁₀ Supplementation in Aging and Disease.

Authors: Juan D Hernández-Camacho; Michel Bernier; Guillermo López-Lluch; Plácido Navas
Journal: Front Physiol Date: 2018-02-05 Impact factor: 4.566

1 in total

Review 1. Coenzyme Q₁₀: Clinical Applications beyond Cardiovascular Diseases.

Authors: Lara Testai; Alma Martelli; Lorenzo Flori; Arrigo F G Cicero; Alessandro Colletti
Journal: Nutrients Date: 2021-05-17 Impact factor: 5.717