Mohamed Hassanein1, Fatheya F Al Awadi2, Khaled El Sayed El Hadidy3, Sobia Sabir Ali4, Akram Echtay5, Khier Djaballah6, Cecile Dessapt-Baradez7, Faris Abdul Kareem Khazaal8, Mohamad Omar Abu-Hijleh9, Abdulrahman Al Shaikh10, Mohamed El Hassan Gharbi11, Naim Shehadeh12, Abdullah Bennakhi13, Monira Al Arouj14. 1. Dubai Hospital, Dubai, United Arab Emirates. Electronic address: mhassanein148@hotmail.com. 2. Dubai Hospital, Dubai, United Arab Emirates. Electronic address: ffAlawadi@dha.gov.ae. 3. Beni Suef University, Beni Suef, Egypt. Electronic address: kshadidy@hotmail.com. 4. Lady Reading Hospital, Peshawar, Pakistan. Electronic address: drsobias@hotmail.com. 5. Rafic Hariri University Hospital, Beirut, Lebanon. Electronic address: Akramechtay@hotmail.com. 6. Sanofi, Paris, France. Electronic address: khier.djaballah@sanofi.com. 7. Sanofi, Guildford, UK. Electronic address: Cecile.Baradez@sanofi.com. 8. Alkindy Obesity Center, Baghdad, Iraq. Electronic address: fariskareem@hotmail.com. 9. Jordan Hospital, Amman, Jordan. Electronic address: dr.omar.clinic@hotmail.com. 10. King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Electronic address: drsh1409@gmail.com. 11. Ibn Sina Hospital, Rabat, Morocco. Electronic address: gharbimohamedelhassan@gmail.com. 12. Rambam Medical Center, Haifa, Israel. Electronic address: n_shehadeh@rambam.health.gov.il. 13. Dasman Diabetes Institute, Kuwait City, Kuwait. Electronic address: abdullah.bennakhi@dasmaninstitute.org. 14. Dasman Diabetes Institute, Kuwait City, Kuwait. Electronic address: monira.arouj@dasmaninstitute.org.
Abstract
AIMS: We aimed to describe the characteristics and care of participants with diabetes during Ramadan in the Middle East and North Africa (MENA). METHODS: In this prospective, observational study, we analysed the number of fasted days, number of participants fasting, glycemic control, rate of hypoglycemic events, and lifestyle patterns for participants with T2DM during Ramadan 2016. RESULTS: The population included 1749 participants with T2DM. The mean (SD) duration of fasting was 27.7 (5.0) days, and 57.3% of participants fasted for the full duration of Ramadan. Following Ramadan, a significant improvement in HbA1c, FPG, and PPG was observed (p < 0.0001). Confirmed hypoglycemia increased significantly from before to during Ramadan (incidence: 4.9% vs. 10.4%, p < 0.001; adverse events: 0.11 vs. 0.22 events/month/participant, p < 0.001) and was dependent on the treatment regimen. Severe hypoglycemia incidence was 0.2% before versus 0.9% during Ramadan (p = 0.031), whereas adverse events remained comparable (0.01 events/month/participant; p = 0.154). Most participants (97.4%) reported lifestyle changes during Ramadan. CONCLUSIONS: This prospective study is the first to describe the characteristics and care of participants with T2DM during Ramadan in MENA, and can be utilized in the development of evidence-based care to ensure the safety of participants who fast.
AIMS: We aimed to describe the characteristics and care of participants with diabetes during Ramadan in the Middle East and North Africa (MENA). METHODS: In this prospective, observational study, we analysed the number of fasted days, number of participants fasting, glycemic control, rate of hypoglycemic events, and lifestyle patterns for participants with T2DM during Ramadan 2016. RESULTS: The population included 1749 participants with T2DM. The mean (SD) duration of fasting was 27.7 (5.0) days, and 57.3% of participants fasted for the full duration of Ramadan. Following Ramadan, a significant improvement in HbA1c, FPG, and PPG was observed (p < 0.0001). Confirmed hypoglycemia increased significantly from before to during Ramadan (incidence: 4.9% vs. 10.4%, p < 0.001; adverse events: 0.11 vs. 0.22 events/month/participant, p < 0.001) and was dependent on the treatment regimen. Severe hypoglycemia incidence was 0.2% before versus 0.9% during Ramadan (p = 0.031), whereas adverse events remained comparable (0.01 events/month/participant; p = 0.154). Most participants (97.4%) reported lifestyle changes during Ramadan. CONCLUSIONS: This prospective study is the first to describe the characteristics and care of participants with T2DM during Ramadan in MENA, and can be utilized in the development of evidence-based care to ensure the safety of participants who fast.
Authors: Syed H Ahmed; Tahseen A Chowdhury; Sufyan Hussain; Ateeq Syed; Ali Karamat; Ahmed Helmy; Salman Waqar; Samina Ali; Ammarah Dabhad; Susan T Seal; Anna Hodgkinson; Shazli Azmi; Nazim Ghouri Journal: Diabetes Ther Date: 2020-09-09 Impact factor: 2.945
Authors: Dana Abdelrahim; MoezAlIslam E Faris; Mohamed Hassanein; Ayman Z Shakir; Ayesha M Yusuf; Aljohara S Almeneessier; Ahmed S BaHammam Journal: Front Endocrinol (Lausanne) Date: 2021-03-08 Impact factor: 5.555
Authors: Louay Y Zaghlol; Amir F Beirat; Justin Z Amarin; Amro M Hassoun Al Najar; Yazan Y Hasan; Abdallah Qtaishat; Michael E Tierney; Raja Y Zaghlol; Ayman A Zayed Journal: Front Endocrinol (Lausanne) Date: 2021-07-07 Impact factor: 5.555