Literature DB >> 30825466

Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function.

Clare Hardman1, Wentao Chen2, Jian Luo2, Paul Batty2, Yi-Ling Chen1, Janina Nahler1, Yanqiu Wu2, Ian D Pavord2, Veit J Erpenbeck3, David A Sandham4, Luzheng Xue2, Graham Ogg5.   

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Year:  2019        PMID： 30825466     DOI： 10.1016/j.jaci.2019.02.015

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


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  5 in total

1.  The Roles of Type 2 Cytotoxic T Cells in Inflammation, Tissue Remodeling, and Prostaglandin (PG) D2 Production Are Attenuated by PGD2 Receptor 2 Antagonism.

Authors:  Wentao Chen; Jian Luo; Yuan Ye; Ryan Hoyle; Wei Liu; Rowie Borst; Shamsah Kazani; Eric A Shikatani; Veit J Erpenbeck; Ian D Pavord; Paul Klenerman; David A Sandham; Luzheng Xue
Journal:  J Immunol       Date:  2021-05-19       Impact factor: 5.422

2.  Efficacy and safety of fevipiprant in patients with uncontrolled asthma: Two replicate, phase 3, randomised, double-blind, placebo-controlled trials (ZEAL-1 and ZEAL-2).

Authors:  Mario Castro; Edward Kerwin; David Miller; Andrew Pedinoff; Lawrence Sher; Pamela Cardenas; Barbara Knorr; David Lawrence; Diego Ossa; Wei Wang; Jorge F Maspero
Journal:  EClinicalMedicine       Date:  2021-04-25

3.  Long-term safety and exploratory efficacy of fevipiprant in patients with inadequately controlled asthma: the SPIRIT randomised clinical trial.

Authors:  Jorge Maspero; Ioana Octavia Agache; Tadashi Kamei; Makoto Yoshida; Bryan Boone; James M Felser; Fernando Kawakami; Barbara Knorr; David Lawrence; Thomas Lehmann; Wei Wang; Andrew J Pedinoff
Journal:  Respir Res       Date:  2021-12-11

4.  Prostaglandin D2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP2 receptor.

Authors:  Saskia Carstensen; Christina Gress; Veit J Erpenbeck; Shamsah D Kazani; Jens M Hohlfeld; David A Sandham; Meike Müller
Journal:  Respir Res       Date:  2021-10-07

Review 5.  The Biology of Prostaglandins and Their Role as a Target for Allergic Airway Disease Therapy.

Authors:  Kijeong Lee; Sang Hag Lee; Tae Hoon Kim
Journal:  Int J Mol Sci       Date:  2020-03-08       Impact factor: 5.923
  5 in total

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