Literature DB >> 30824529

If you build it, they will come: Reaching across the "IL" with Neo-2/15.

Kelly Andrews1, Asha Pillai1.   

Abstract

A computationally designed mimic of interleukin-2 (IL-2) selectively expands cytotoxic CD8+ T cells over regulatory T cells and supports antitumor immunity.
Copyright © 2019, American Association for the Advancement of Science.

Entities:  

Year:  2019        PMID： 30824529      PMCID： PMC7828460          DOI： 10.1126/sciimmunol.aax1017

Source DB:  PubMed          Journal:  Sci Immunol        ISSN： 2470-9468


  1 in total

1.  De novo design of potent and selective mimics of IL-2 and IL-15.

Authors:  Daniel-Adriano Silva; Shawn Yu; Umut Y Ulge; Jamie B Spangler; Kevin M Jude; Carlos Labão-Almeida; Lestat R Ali; Alfredo Quijano-Rubio; Mikel Ruterbusch; Isabel Leung; Tamara Biary; Stephanie J Crowley; Enrique Marcos; Carl D Walkey; Brian D Weitzner; Fátima Pardo-Avila; Javier Castellanos; Lauren Carter; Lance Stewart; Stanley R Riddell; Marion Pepper; Gonçalo J L Bernardes; Michael Dougan; K Christopher Garcia; David Baker
Journal:  Nature       Date:  2019-01-09       Impact factor: 49.962
  1 in total

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