Laura Andrea Rodríguez-Villamizar1, Néstor Yezid Rojas-Roa2, Julián Alfredo Fernández-Niño3. 1. Public Health Department, School of Medicine, Santander Industrial University, Bucaramanga, Colombia. Electronic address: laurovi@uis.edu.co. 2. School of Engineering, National University of Colombia, Bogota, Colombia. Electronic address: nyrojas@unal.edu.co. 3. Public Health Department, North University, Barranquilla, Colombia. Electronic address: aninoj@uninorte.edu.co.
Abstract
BACKGROUND: We evaluated the short-term effect of mixtures of ambient air pollutants on respiratory and circulatory morbidity in four Colombian cities. METHODS: Daily Emergency Department (ED) visit records for respiratory and circulatory selected diagnosis and daily concentrations for six criteria air pollutant were obtained in four of the five major cities in Colombia: Bucaramanga, Bogota, Cali, and Medellin during 2011-2014. Using conditional Poisson time series analysis with fixed effects, we assessed the effect of air pollutants on health outcomes using single-pollutant, two-pollutant and specific mixtures-of-pollutant models controlling for meteorology and time trends. The percentages of change in the rate of ED visits and their 95% confidence interval were estimated for the joint effect of pollutants. RESULTS: In single-pollutant models increases in gases concentrations were associated with increases in ED visits for respiratory and circulatory diseases. The two-pollutant models for respiratory diseases showed that the effect of NO2 alone (% change 2.86 95% CI 1.87-3.85) is higher than the joint effect of any of its combinations except for its combination with SO2 (% change 3.05 95%CI 1.04-5.05). The two-pollutant models for circulatory diseases showed synergistic effects between NO2 and PM2.5 (% change 2.13 95%CI 0.001-4.26). Specific mixtures models showed that the mixture of "traffic-related pollutants" has the higher joint effect on circulatory morbidity and respiratory morbidity. CONCLUSIONS: The results show the dominant effect of NO2 in air pollution mixtures on respiratory and circulatory morbidity, and the synergistic effect of NO2 and SO2 in air pollution mixtures on respiratory morbidity.
BACKGROUND: We evaluated the short-term effect of mixtures of ambient air pollutants on respiratory and circulatory morbidity in four Colombian cities. METHODS: Daily Emergency Department (ED) visit records for respiratory and circulatory selected diagnosis and daily concentrations for six criteria air pollutant were obtained in four of the five major cities in Colombia: Bucaramanga, Bogota, Cali, and Medellin during 2011-2014. Using conditional Poisson time series analysis with fixed effects, we assessed the effect of air pollutants on health outcomes using single-pollutant, two-pollutant and specific mixtures-of-pollutant models controlling for meteorology and time trends. The percentages of change in the rate of ED visits and their 95% confidence interval were estimated for the joint effect of pollutants. RESULTS: In single-pollutant models increases in gases concentrations were associated with increases in ED visits for respiratory and circulatory diseases. The two-pollutant models for respiratory diseases showed that the effect of NO2 alone (% change 2.86 95% CI 1.87-3.85) is higher than the joint effect of any of its combinations except for its combination with SO2 (% change 3.05 95%CI 1.04-5.05). The two-pollutant models for circulatory diseases showed synergistic effects between NO2 and PM2.5 (% change 2.13 95%CI 0.001-4.26). Specific mixtures models showed that the mixture of "traffic-related pollutants" has the higher joint effect on circulatory morbidity and respiratory morbidity. CONCLUSIONS: The results show the dominant effect of NO2 in air pollution mixtures on respiratory and circulatory morbidity, and the synergistic effect of NO2 and SO2 in air pollution mixtures on respiratory morbidity.
Authors: Laura Andrea Rodríguez-Camargo; Ronal Jackson Sierra-Parada; Luis Camilo Blanco-Becerra Journal: Biomedica Date: 2020-03-01 Impact factor: 0.935
Authors: Dayana Milena Agudelo-Castañeda; Elba Calesso Teixeira; Larissa Alves; Julián Alfredo Fernández-Niño; Laura Andrea Rodríguez-Villamizar Journal: Int J Environ Res Public Health Date: 2019-10-09 Impact factor: 3.390
Authors: Laura A Rodriguez-Villamizar; Luis Carlos Belalcázar-Ceron; Julián Alfredo Fernández-Niño; Diana Marcela Marín-Pineda; Oscar Alberto Rojas-Sánchez; Lizbeth Alexandra Acuña-Merchán; Nathaly Ramírez-García; Sonia Cecilia Mangones-Matos; Jorge Mario Vargas-González; Julián Herrera-Torres; Dayana Milena Agudelo-Castañeda; Juan Gabriel Piñeros Jiménez; Néstor Y Rojas-Roa; Victor Mauricio Herrera-Galindo Journal: Sci Total Environ Date: 2020-11-26 Impact factor: 7.963
Authors: Jeadran N Malagon-Rojas; Diana Carolina Pinzón-Silva; Luisa F Lagos M; Yesith Guillermo Toloza-Perez; Eliana L Parra; Luis Jorge Hernández Florez; Ricardo Morales Betancourt; Sol Angie Romero; Ana Paola Ríos Cabra; Olga L Sarmiento Journal: JMIR Res Protoc Date: 2022-01-31