| Literature DB >> 30822136 |
Pei-Liang Zhang1, Gang Wang1,2, Feng-Qing Xu1,2,3, Jin-Song Liu1,2, Ju-Tao Wang1,2, Rui Zhang1, Hai-Tao Liu1, Jiang-Miao Hu3, Guo-Kai Wang1,2, Pei-Yun Wu1,2.
Abstract
A new steroid lactone aspergilolide (1), and nine known compounds helvolic acid (2), verruculogen (3), tryprostatin B (4), 13-oxofumitremorgin B (5), fumitremorgin C (6), demethoxy fumitremorgin C (7), terezine D (8), aszonalenin (9), 12, 13-dihydroxy-fumitremorgin C (10) from cultures of the endophytic fungus Aspergillus sp. MBL1612. Their chemical structures were determined by a series of extensive spectroscopic methods. All of the compounds were isolated from this genus for the first time. The cytotoxicity against five human cancer cell lines of new compound were detected.Entities:
Keywords: . MBL1612; Edophytic fungus; aspergilolide; cytotoxicity
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Year: 2018 PMID： 30822136 DOI： 10.1080/14786419.2018.1488706
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861