Literature DB >> 30821310

An ROS-responsive and self-accelerating drug release nanoplatform for overcoming multidrug resistance.

Xueming Lv1, Yiyong Zhu, Hamidreza Ghandehari, Ao Yu, Yongjian Wang.   

Abstract

An 'on-demand' drug release and ROS-responsive nanoparticle was prepared by chemically conjugating hydrophobic α-tocopheryl succinate to hydrophilic poly(ethylene glycol) via a thioketal linker. This nanoparticle encapsulated with doxorubicin and α-tocopheryl succinate exhibited remarkable efficiency in reversing multidrug resistance both in vitro and in vivo.

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Year:  2019        PMID： 30821310     DOI： 10.1039/c9cc00358d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  A pH-Responsive Charge-Reversal Drug Delivery System with Tumor-Specific Drug Release and ROS Generation for Cancer Therapy.

Authors:  Chen Xu; Rijin Song; Pei Lu; Jianchun Chen; Yongqiang Zhou; Gang Shen; Minjun Jiang; Wei Zhang
Journal:  Int J Nanomedicine       Date:  2020-01-08

2.  Reactive Oxygen Species-Responsive Miktoarm Amphiphile for Triggered Intracellular Release of Anti-Cancer Therapeutics.

Authors:  Hyun-Chul Kim; Eunjoo Kim; Se Guen Lee; Sung Jun Lee; Sang Won Jeong; Young Jae Lee; Mi Kyung Kwon; Seong-Kyoon Choi; Jun Seong Hwang; Eunsook Choi
Journal:  Polymers (Basel)       Date:  2021-12-16       Impact factor: 4.329

3.  Ultrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes.

Authors:  Yitong Guo; Zhuo Wan; Ping Zhao; Mengying Wei; Yunnan Liu; Te Bu; Wenqi Sun; Zhelong Li; Lijun Yuan
Journal:  J Nanobiotechnology       Date:  2021-12-04       Impact factor: 10.435

Review 4.  Recent advances in functionalized upconversion nanoparticles for light-activated tumor therapy.

Authors:  Hongqian Chu; Tingming Cao; Guangming Dai; Bei Liu; Huijuan Duan; Chengcheng Kong; Na Tian; Dailun Hou; Zhaogang Sun
Journal:  RSC Adv       Date:  2021-11-03       Impact factor: 4.036

Review 5.  The Use of Iron Oxide Nanoparticles to Reprogram Macrophage Responses and the Immunological Tumor Microenvironment.

Authors:  Vladimir Mulens-Arias; José Manuel Rojas; Domingo F Barber
Journal:  Front Immunol       Date:  2021-06-09       Impact factor: 7.561
  5 in total

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