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Literature DB >> 3082067

Involucrin expression in adnexal skin tumours. An immunohistological study.

J Kanitakis, G Zambruno, J Viac, J Thivolet.

Abstract

The expression of involucrin was studied in a group of skin neoplasms, mostly of adnexal origin. As happens with other types of epithelial tumours, involucrin was detected in the most differentiated areas (presenting a squamoid or ductal differentiation). No reactivity was observed in non-epithelial skin tumours. These results suggest that involucrin is a specific marker for epithelial and adnexal differentiation of skin tumours and may thus be a useful aid in histopathologic diagnosis and classification of neoplasms.

Entities: Disease Gene

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Year: 1986 PMID： 3082067 DOI： 10.1007/bf00705306

Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398

11 in total

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7. Involucrin, a marker of squamous and urothelial differentiation. An immunohistochemical study on its distribution in normal and neoplastic tissues.

Authors: A E Walts; J W Said; M B Siegel; S Banks-Schlegel
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Involucrin expression in adnexal skin tumours. An immunohistological study.

1. Merkel cells express desmosomal proteins and cytokeratins.

Review 2. Neuroendocrine (Merkel) cells of the skin: hyperplasias, dysplasias, and neoplasms.

3. Stewart-Treves syndrome: an histogenetic (ultrastructural and immunohistological) study.

4. Abnormal maturation pathway of keratinocytes in psoriatic skin.

5. Identification of Merkel cells in human skin by specific cytokeratin antibodies: changes of cell density and distribution in fetal and adult plantar epidermis.

6. Postmastectomy angiosarcoma (Stewart-Treves syndrome). Light-microscopic, immunohistological, and ultrastructural characteristics of two cases.

7. Involucrin, a marker of squamous and urothelial differentiation. An immunohistochemical study on its distribution in normal and neoplastic tissues.

8. Involucrin in squamous and basal cell carcinomas of the skin: an immunohistochemical study.

9. Involucrin expression in normal and neoplastic human skin: a marker for keratinocyte differentiation.

10. Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia.

1. Involucrin expression in breast carcinomas: an immunohistochemical study.

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