Literature DB >> 30820644

Population genetic data of 30 insertion-deletion markers in Punjabi population of Pakistan.

Muhammad Shahzad1, Manzoor Hussain2, Muhammad Shafique3, Rukhsana Perveen2, Nadeem Sheikh2.   

Abstract

Insertion-deletion polymorphism (Indels) is valuable diallelic markers for forensic as well as parentage analysis. The Investigator DIPplex Kit (Qiagen) contains thirty autosomal Indels markers along with amelogenin. These thirty markers were tested in the Pakistani Punjabi Population but no significant deviations were observed from Hardy-Weinberg equilibrium rule expectations (Bonferroni corrected) except HLD58, HLD56, HLD99, and HLD40. The mean expected and observed heterozygosity was found 0.4701 and 0.4667 respectively; combined matching probability was computed as 7.31867 × 10-13. However, the use of the 30 Indels markers proved to be a good supplementary tool in forensic casework, particularly when evidence sample is highly degraded. The significant genetic differences were also observed between the Punjabi and other populations of the world.

Entities:  

Keywords:  Forensic parameters; Indels; Pakistan; Punjabi population

Year:  2019        PMID: 30820644     DOI: 10.1007/s00414-019-02029-w

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  8 in total

1.  Forensic performance of Investigator DIPplex indels genotyping kit in native, immigrant, and admixed populations in South Africa.

Authors:  Gwynneth Hefke; Sean Davison; Maria Eugenia D'Amato
Journal:  Electrophoresis       Date:  2015-12       Impact factor: 3.535

2.  PowerMarker: an integrated analysis environment for genetic marker analysis.

Authors:  Kejun Liu; Spencer V Muse
Journal:  Bioinformatics       Date:  2005-02-10       Impact factor: 6.937

3.  Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows.

Authors:  Laurent Excoffier; Heidi E L Lischer
Journal:  Mol Ecol Resour       Date:  2010-03-01       Impact factor: 7.090

4.  Extraction of DNA from Skeletal Remains.

Authors:  Suni M Edson; Timothy P McMahon
Journal:  Methods Mol Biol       Date:  2016

5.  DNA fingerprinting: improved DNA extraction from small blood samples.

Authors:  E Signer; C C Kuenzle; P E Thomann; U Hübscher
Journal:  Nucleic Acids Res       Date:  1988-08-11       Impact factor: 16.971

6.  Human diallelic insertion/deletion polymorphisms.

Authors:  James L Weber; Donna David; Jeremy Heil; Ying Fan; Chengfeng Zhao; Gabor Marth
Journal:  Am J Hum Genet       Date:  2002-09-04       Impact factor: 11.025

7.  A new multiplex for human identification using insertion/deletion polymorphisms.

Authors:  Rui Pereira; Christopher Phillips; Cíntia Alves; António Amorim; Angel Carracedo; Leonor Gusmão
Journal:  Electrophoresis       Date:  2009-11       Impact factor: 3.535

8.  ALFRED: an allele frequency resource for research and teaching.

Authors:  Haseena Rajeevan; Usha Soundararajan; Judith R Kidd; Andrew J Pakstis; Kenneth K Kidd
Journal:  Nucleic Acids Res       Date:  2011-10-28       Impact factor: 16.971

  8 in total

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