Literature DB >> 30819920

Adult patients with de novo acute myeloid leukemia show a functional deregulation of redox balance at diagnosis which is correlated with molecular subtypes and overall survival.

Julie Mondet1,2, Caroline Lo Presti2,3, Catherine Garrel4, Kristina Skaare5, Clara Mariette6, Sylvain Carras7, Sophie Park2,6, Martin Carré6, Claude-Eric Bulabois6, Lysiane Molina6, Rémy Gressin6, Anne Thiebaut6, Stéphane Courby6, Nuria Socoro-Yuste8, Patrice Faure4, Anne Mc Leer-Florin9,2, Jean-Yves Cahn2,6, Pascal Mossuz10,3.   

Abstract

Entities:  

Year:  2019        PMID： 30819920      PMCID： PMC6717570          DOI： 10.3324/haematol.2018.206821

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  14 in total

1.  AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress.

Authors:  Shrivani Sriskanthadevan; Danny V Jeyaraju; Timothy E Chung; Swayam Prabha; Wei Xu; Marko Skrtic; Bozhena Jhas; Rose Hurren; Marcela Gronda; Xiaoming Wang; Yulia Jitkova; Mahadeo A Sukhai; Feng-Hsu Lin; Neil Maclean; Rob Laister; Carolyn A Goard; Peter J Mullen; Stephanie Xie; Linda Z Penn; Ian M Rogers; John E Dick; Mark D Minden; Aaron D Schimmer
Journal:  Blood       Date:  2015-01-28       Impact factor: 22.113

2.  The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.

Authors:  Jianbiao Zhou; Chonglei Bi; Lip-Lee Cheong; Sylvia Mahara; Shaw-Cheng Liu; Kian-Ghee Tay; Tze-Loong Koh; Qiang Yu; Wee-Joo Chng
Journal:  Blood       Date:  2011-07-06       Impact factor: 22.113

3.  Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model.

Authors:  Sergey A Sinenko; Tony Hung; Tatiana Moroz; Quynh-Minh Tran; Sohrab Sidhu; Matthew D Cheney; Nancy A Speck; Utpal Banerjee
Journal:  Blood       Date:  2010-08-05       Impact factor: 22.113

4.  Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis.

Authors:  Johan Aurelius; Fredrik B Thorén; Ali A Akhiani; Mats Brune; Lars Palmqvist; Markus Hansson; Kristoffer Hellstrand; Anna Martner
Journal:  Blood       Date:  2012-05-01       Impact factor: 22.113

5.  Diphenyleneiodonium inhibits the cell redox metabolism and induces oxidative stress.

Authors:  Chiara Riganti; Elena Gazzano; Manuela Polimeni; Costanzo Costamagna; Amalia Bosia; Dario Ghigo
Journal:  J Biol Chem       Date:  2004-09-09       Impact factor: 5.157

6.  BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.

Authors:  Eleni D Lagadinou; Alexander Sach; Kevin Callahan; Randall M Rossi; Sarah J Neering; Mohammad Minhajuddin; John M Ashton; Shanshan Pei; Valerie Grose; Kristen M O'Dwyer; Jane L Liesveld; Paul S Brookes; Michael W Becker; Craig T Jordan
Journal:  Cell Stem Cell       Date:  2013-01-17       Impact factor: 24.633

7.  Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML.

Authors:  Annahita Sallmyr; Jinshui Fan; Kamal Datta; Kyu-Tae Kim; Dan Grosu; Paul Shapiro; Donald Small; Feyruz Rassool
Journal:  Blood       Date:  2008-01-11       Impact factor: 22.113

8.  Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.

Authors:  Shanshan Pei; Mohammad Minhajuddin; Kevin P Callahan; Marlene Balys; John M Ashton; Sarah J Neering; Eleni D Lagadinou; Cheryl Corbett; Haobin Ye; Jane L Liesveld; Kristen M O'Dwyer; Zheng Li; Lei Shi; Patricia Greninger; Jeffrey Settleman; Cyril Benes; Fred K Hagen; Joshua Munger; Peter A Crooks; Michael W Becker; Craig T Jordan
Journal:  J Biol Chem       Date:  2013-10-02       Impact factor: 5.157

9.  Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling.

Authors:  Paul S Hole; Joanna Zabkiewicz; Chinmay Munje; Zarabeth Newton; Lorna Pearn; Paul White; Nuria Marquez; Robert K Hills; Alan K Burnett; Alex Tonks; Richard L Darley
Journal:  Blood       Date:  2013-10-02       Impact factor: 22.113

10.  The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

Authors:  Patrick S Ward; Jay Patel; David R Wise; Omar Abdel-Wahab; Bryson D Bennett; Hilary A Coller; Justin R Cross; Valeria R Fantin; Cyrus V Hedvat; Alexander E Perl; Joshua D Rabinowitz; Martin Carroll; Shinsan M Su; Kim A Sharp; Ross L Levine; Craig B Thompson
Journal:  Cancer Cell       Date:  2010-02-18       Impact factor: 38.585
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  4 in total

1.  The differential activation of metabolic pathways in leukemic cells depending on their genotype and micro-environmental stress.

Authors:  Caroline Lo Presti; Florence Fauvelle; Julie Mondet; Pascal Mossuz
Journal:  Metabolomics       Date:  2020-01-10       Impact factor: 4.290

2.  The metabolic reprogramming in acute myeloid leukemia patients depends on their genotype and is a prognostic marker.

Authors:  Caroline Lo Presti; Florence Fauvelle; Marie-Christine Jacob; Julie Mondet; Pascal Mossuz
Journal:  Blood Adv       Date:  2021-01-12

3.  Diphenyleneiodonium Triggers Cell Death of Acute Myeloid Leukemia Cells by Blocking the Mitochondrial Respiratory Chain, and Synergizes with Cytarabine.

Authors:  Hassan Dakik; Maya El Dor; Jérôme Bourgeais; Farah Kouzi; Olivier Herault; Fabrice Gouilleux; Kazem Zibara; Frédéric Mazurier
Journal:  Cancers (Basel)       Date:  2022-05-18       Impact factor: 6.575

4.  VAS3947 Induces UPR-Mediated Apoptosis through Cysteine Thiol Alkylation in AML Cell Lines.

Authors:  Maya El Dor; Hassan Dakik; Marion Polomski; Eloi Haudebourg; Marie Brachet; Fabrice Gouilleux; Gildas Prié; Kazem Zibara; Frédéric Mazurier
Journal:  Int J Mol Sci       Date:  2020-07-31       Impact factor: 5.923
  4 in total

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