Literature DB >> 30814474

Multidisciplinary Tumor Board Recommendations for Oligometastatic Malignancies: A Prospective Single-Center Analysis.

Christian Galata, Elisabeth Wimmer, Bernd Kasper, Frederik Wenz, Christoph Reißfelder, Jens Jakob.   

Abstract

BACKGROUND: The treatment of oligometastatic disease is challenging and few data exist to guide treatment decisions. The objective of this study was to improve the data on the prevalence and treatment of patients with oligometastatic disease.
METHODS: We conducted a prospective single-center analysis that included all consecutive patients discussed in multidisciplinary tumor boards (MDT) between February and July 2017. Patients with oligometastatic disease were identified and treatment strategies were evaluated.
RESULTS: 1,673 patients were included in this study, 609 (36.4%) presented with metastatic disease, 151 (9%) had oligometastatic disease. Common metastatic sites were brain, liver, and lung. Lung cancer patients were the largest cohort (20.5%) among all patients with oligometastatic disease compared with other tumor entities. The majority of oligometastatic patients (68.9%) received local treatment with or without additional chemotherapy, 17.9% were recommended systemic therapy alone. MDT recommended watchful waiting for 4.6% of the patients.
CONCLUSION: Patients with oligometastatic disease represent a considerable proportion of all patients in MDT. In this study, 68.9% of patients with oligometastatic disease received regional treatment. This shows a possible treatment shift from palliative to potentially curative intent. These data may be used to design prospective clinical trials to optimize the treatment of oligometastatic disease.
© 2019 S. Karger AG, Basel.

Entities:  

Keywords:  Interventional therapy; Multidisciplinary tumor board; Oligometastases; Radiation therapy; Surgery

Mesh:

Substances:

Year:  2019        PMID: 30814474     DOI: 10.1159/000495474

Source DB:  PubMed          Journal:  Oncol Res Treat        ISSN: 2296-5270            Impact factor:   2.825


  4 in total

1.  The radical approach to the oligometastatic not small cell lung cancer patient: which? how? when? where?

Authors:  Luca Bertolaccini; Lorenzo Spaggiari
Journal:  J Thorac Dis       Date:  2019-09       Impact factor: 2.895

Review 2.  Oligometastatic Disease Management: Finding the Sweet Spot.

Authors:  Petr Szturz; Daan Nevens; Jan B Vermorken
Journal:  Front Oncol       Date:  2020-12-22       Impact factor: 6.244

Review 3.  Multidisciplinary team care in advanced lung cancer.

Authors:  Anna Kowalczyk; Jacek Jassem
Journal:  Transl Lung Cancer Res       Date:  2020-08

Review 4.  Optimizing lung cancer MDT data for maximum clinical impact-a scoping literature review.

Authors:  Emily Stone; Nicole Rankin; David Currow; Kwun M Fong; Jane L Phillips; Tim Shaw
Journal:  Transl Lung Cancer Res       Date:  2020-08
  4 in total

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