| Literature DB >> 30811806 |
Zhang-Qiao Xie1,2, Lin-Fen Ding1, De-Sheng Wang1,2, Wei Nie1,2, Jiang-Xin Liu2, Jing Qin2, Liu-Dong Song1, Xing-De Wu2, Qin-Shi Zhao2.
Abstract
Thirteen sesquiterpenes including eight new ones, magnodelavins A-H (1-8), were obtained from the 95 % ethanolic extract of the leaves of Magnolia delavayi Franch. The structures of the new compounds were determined by exhaustive 1 H-, 13 C-, 2D-NMR, UV, IR, and HR-ESI-MS data, as well as X-ray crystallographic analysis. Compounds 9 and 10 showed potent cytotoxic activities against HL-60, A-549, SMMC-7721, MCF-7, and SW480 human cancer cell lines in vitro using MTS assay.Entities:
Keywords: Magnolia delavayi; cytotoxicity; phytochemistry; sesquiterpene; structure elucidation
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Year: 2019 PMID： 30811806 DOI： 10.1002/cbdv.201900013
Source DB: PubMed Journal: Chem Biodivers ISSN： 1612-1872 Impact factor: 2.408