Literature DB >> 3081113

Prostacyclin deficiency in a young woman with recurrent thrombosis.

J G Lanham, M Levin, Z Brown, A E Gharavi, P A Thomas, G C Hanson.   

Abstract

A young woman with recurrent deep venous thromboses and spontaneous abortions was studied. She suffered an ovarian infarction followed by aortic thrombosis and renal failure. Evidence for deficient prostacyclin production was found and she responded to treatment with a prostacyclin infusion. This syndrome is identical with that seen in women with the lupus anticoagulant, but the lupus anticoagulant was not detected and no other cause was identified.

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Year:  1986        PMID： 3081113      PMCID： PMC1339420          DOI： 10.1136/bmj.292.6518.435

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN： 0267-0623


  11 in total

1.  Arterial thrombosis, intrauterine death and "lupus" antiocoagulant: detection of immunoglobulin interfering with prostacyclin formation.

Authors:  L O Carreras; G Defreyn; S J Machin; J Vermylen; R Deman; B Spitz; A Van Assche
Journal:  Lancet       Date:  1981-01-31       Impact factor: 79.321

2.  "Lupus" anticoagulant and thrombosis--possible role of inhibition of prostacyclin formation.

Authors:  L O Carreras; J G Vermylen
Journal:  Thromb Haemost       Date:  1982-08-24       Impact factor: 5.249

3.  Acute aortic thrombosis in antithrombin III deficiency.

Authors:  M E Shapiro; R Rodvien; K A Bauer; E W Salzman
Journal:  JAMA       Date:  1981-05-01       Impact factor: 56.272

4.  Homocystinuria presenting as multiple arterial occlusions.

Authors:  G Newman; J R Mitchell
Journal:  Q J Med       Date:  1984

5.  Decrease prostacyclin production: a characteristic of chronic placental insufficiency syndromes.

Authors:  M J Stuart; D A Clark; S G Sunderji; J B Allen; T Yambo; H Elrad; J H Slott
Journal:  Lancet       Date:  1981-05-23       Impact factor: 79.321

6.  Thrombosis in systemic lupus erythematosus: striking association with the presence of circulating lupus anticoagulant.

Authors:  M L Boey; C B Colaco; A E Gharavi; K B Elkon; S Loizou; G R Hughes
Journal:  Br Med J (Clin Res Ed)       Date:  1983-10-08

7.  Fetal survival after prednisone suppression of maternal lupus-anticoagulant.

Authors:  W F Lubbe; W S Butler; S J Palmer; G C Liggins
Journal:  Lancet       Date:  1983-06-18       Impact factor: 79.321

8.  Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus.

Authors:  E N Harris; A E Gharavi; M L Boey; B M Patel; C G Mackworth-Young; S Loizou; G R Hughes
Journal:  Lancet       Date:  1983-11-26       Impact factor: 79.321

9.  Inhibitor of prostacyclin production in sporadic haemolytic uraemic syndrome.

Authors:  M Levin; K B Elkon; T J Nokes; A M Buckle; M J Dillon; R M Hardisty; T M Barratt
Journal:  Arch Dis Child       Date:  1983-09       Impact factor: 3.791

10.  Monoclonal immunoglobulin M lambda coagulation inhibitor with phospholipid specificity. Mechanism of a lupus anticoagulant.

Authors:  P Thiagarajan; S S Shapiro; L De Marco
Journal:  J Clin Invest       Date:  1980-09       Impact factor: 14.808
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