Intravenous antibiotics at home.

Intravenous antibiotics can be administered safely and effectively and at substantially less cost in a home environment. Patients who are candidates for this treatment must be in stable condition clinically, possess a ready venous access, and show the mental and physical capabilities required to administer intravenous medication. Antibiotics must be delivered promptly and retain their sterility and activity until infusion. Close monitoring of the patient during therapy is essential. Orthopedic infections, mainly osteomyelitis, septic arthritis, and bursitis, have thus far been our most frequently treated infections, with Staphylococcus aureus, aerobic gram-negative bacilli, and S epidermidis the most commonly encountered pathogens. Penicillins, cephalosporins and aminoglycosides have been given most often. Cure rates have exceeded 85%, and many patients resume usual activities during treatment. Complications are unusual, cost savings are substantial, and patient satisfaction is maximal.