| Literature DB >> 30807242 |
Solmaz Maleki Dizaj1, Simin Sharifi1, Elham Ahmadian1, Aziz Eftekhari2, Khosro Adibkia3, Farzaneh Lotfipour3,4.
Abstract
INTRODUCTION: In recent years, the applications of calcium carbonate (CaCO3) nanoparticles (NPs) have gained extensive interest as targeted drug/gene delivery systems to cancerous tissues and cells due to their accessibility, low cost, safety, biocompatibility, pH-sensitivity, and slow biodegradability. AREAS COVERED: Drug-loaded CaCO3 NPs (CCNPs) have been reviewed. An updated search on the current state of CCNPs as cancer drug/gene delivery systems with a focus on their special properties including pH-sensitivity, biodegradability, and sustained release performance has been also assessed. EXPERT OPINION: Based on the reviewed literature, CCNPs, because of their superior features, will have a great aiding role in safe and efficient cancer treatment in the near future.Entities:
Keywords: CaCO nanoparticles; cancer; drug delivery; gene delivery
Mesh:
Substances:
Year: 2019 PMID: 30807242 DOI: 10.1080/17425247.2019.1587408
Source DB: PubMed Journal: Expert Opin Drug Deliv ISSN: 1742-5247 Impact factor: 6.648