Literature DB >> 30807111

Impact of DNA Oxidation on Toxicology: From Quantification to Genomics.

Junzhou Wu1, Shana J Sturla1, Cynthia J Burrows2, Aaron M Fleming2.   

Abstract

Understanding the toxicological implications of deoxyribonucleic acid (DNA) oxidation arising from cellular oxidative stress depends on identifying DNA oxidation products, their location in the genome, and their interaction with repair, replication, and gene expression.

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Year:  2019        PMID： 30807111      PMCID： PMC6429904          DOI： 10.1021/acs.chemrestox.9b00046

Source DB:  PubMed          Journal:  Chem Res Toxicol        ISSN： 0893-228X            Impact factor:   3.739


  6 in total

1.  Sequencing the Mouse Genome for the Oxidatively Modified Base 8-Oxo-7,8-dihydroguanine by OG-Seq.

Authors:  Yun Ding; Aaron M Fleming; Cynthia J Burrows
Journal:  J Am Chem Soc       Date:  2017-02-13       Impact factor: 15.419

2.  Nucleotide-Resolution Genome-Wide Mapping of Oxidative DNA Damage by Click-Code-Seq.

Authors:  Junzhou Wu; Maureen McKeague; Shana J Sturla
Journal:  J Am Chem Soc       Date:  2018-07-26       Impact factor: 15.419

3.  A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.

Authors:  Alessandra Viel; Alessandro Bruselles; Ettore Meccia; Mara Fornasarig; Michele Quaia; Vincenzo Canzonieri; Eleonora Policicchio; Emanuele Damiano Urso; Marco Agostini; Maurizio Genuardi; Emanuela Lucci-Cordisco; Tiziana Venesio; Aline Martayan; Maria Grazia Diodoro; Lupe Sanchez-Mete; Vittoria Stigliano; Filomena Mazzei; Francesca Grasso; Alessandro Giuliani; Marta Baiocchi; Roberta Maestro; Giuseppe Giannini; Marco Tartaglia; Ludmil B Alexandrov; Margherita Bignami
Journal:  EBioMedicine       Date:  2017-04-13       Impact factor: 8.143

4.  8-Oxo-7,8-dihydroguanine in the Context of a Gene Promoter G-Quadruplex Is an On-Off Switch for Transcription.

Authors:  Aaron M Fleming; Judy Zhu; Yun Ding; Cynthia J Burrows
Journal:  ACS Chem Biol       Date:  2017-08-28       Impact factor: 5.100

5.  Genome-wide mapping of 8-oxo-7,8-dihydro-2'-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells.

Authors:  Stefano Amente; Giacomo Di Palo; Giovanni Scala; Tiziana Castrignanò; Francesca Gorini; Sergio Cocozza; Angela Moresano; Piero Pucci; Bin Ma; Irina Stepanov; Luigi Lania; Pier Giuseppe Pelicci; Gaetano Ivan Dellino; Barbara Majello
Journal:  Nucleic Acids Res       Date:  2019-01-10       Impact factor: 16.971

6.  Identification of DNA lesions using a third base pair for amplification and nanopore sequencing.

Authors:  Jan Riedl; Yun Ding; Aaron M Fleming; Cynthia J Burrows
Journal:  Nat Commun       Date:  2015-11-06       Impact factor: 14.919
  6 in total
  2 in total

Review 1.  Roles of OGG1 in transcriptional regulation and maintenance of metabolic homeostasis.

Authors:  Harini Sampath; R Stephen Lloyd
Journal:  DNA Repair (Amst)       Date:  2019-07-08

Review 2.  Ultrafast Processes Occurring in Radiolysis of Highly Concentrated Solutions of Nucleosides/Tides.

Authors:  Jun Ma; Sergey A Denisov; Amitava Adhikary; Mehran Mostafavi
Journal:  Int J Mol Sci       Date:  2019-10-08       Impact factor: 5.923
  2 in total

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