Literature DB >> 30807001

The Iridoid Myodesert-1-ene and Elemol/Eudesmol are found in Distinct Chemotypes of the Australian Aboriginal Medicinal Plant Eremophila dalyana (Scrophulariaceae).

Nicholas J Sadgrove, Timothy L Collins, Sarah V A-M Legendre, Julian Klepp, Graham L Jones, Ben W Greatrex.   

Abstract

The strongly aromatic Australian desert species Eremophila dalyana is an Aboriginal medicinal plant that continues to be used today in Central Australia in the treatment of respiratory complaints and Sarcoptes scabiei infestation. Using hydrodistillation of aerial parts of the plant, the new natural product myodesert-l- ene was isolated in two disjunct populations at up to 98% of the volatiles present in the hydrodistilled oils. Weak antimicrobial activities were observed for whole oils and myodesert-l-ene. Activities in the hydrodistilled oil were attributed to the antimicrobial sesquiterpenes elemol and eudesmol which showed good activity when isolated and were relatively abundant in the chemotype used medicinally. The biogenesis of myodesert-l-ene from iridodial is proposed.

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Year:  2016        PMID: 30807001

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  3 in total

1.  Density-functional theory of the catnip molecule, nepetalactone.

Authors:  Syed Lal Badshah; Rabiya Jehan
Journal:  Mol Cell Biochem       Date:  2022-01-25       Impact factor: 3.396

2.  Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila.

Authors:  Oliver Gericke; Rachael M Fowler; Allison M Heskes; Michael J Bayly; Susan J Semple; Chi P Ndi; Dan Staerk; Claus J Løland; Daniel J Murphy; Bevan J Buirchell; Birger Lindberg Møller
Journal:  Plant J       Date:  2021-09-16       Impact factor: 7.091

Review 3.  Fundamental Chemistry of Essential Oils and Volatile Organic Compounds, Methods of Analysis and Authentication.

Authors:  Nicholas J Sadgrove; Guillermo F Padilla-González; Methee Phumthum
Journal:  Plants (Basel)       Date:  2022-03-16
  3 in total

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