| Literature DB >> 30805967 |
Wenpeng Zhang1,2, Spencer Chiang1,2, Zishuai Li1, Qinhua Chen3, Yu Xia4, Zheng Ouyang1,2.
Abstract
A porous polymer coating transfer enrichment method is developed for the direct mass spectrometry (MS) analysis of lipids. The enrichment is fast (ca. 1 min) and enables the profiling and quantitation of lipids in small-volume biofluid samples. Coupled with a photochemical Paternò-Büchi reaction, this method enables the fast determination of lipid structure at the C=C location level and point-of-care lipid biomarker analysis.Entities:
Keywords: analyte enrichment; biofluids; lipid isomers; mass spectrometry; polymer coatings
Year: 2019 PMID: 30805967 PMCID: PMC6541494 DOI: 10.1002/anie.201900011
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336