Literature DB >> 30805889

Primary hyperparathyroidism due to ectopic parathyroid adenoma in an adolescent: a case report and review of the literature.

Xiangli Liu1, Lei Sun1, Mingrui Shao1, PeiWen Li1, Wenke Liu1, Xinyu Zhang1, Lin Zhang1, Yingjun Ma2, Wenya Li3.   

Abstract

PURPOSE: Primary hyperparathyroidism (PHPT) is a common endocrine disorder and is usually diagnosed in adults. PHPT due to ectopic parathyroid adenoma in adolescents is rare.
METHODS: We describe the case of a 15-year-old boy with PHPT due to ectopic parathyroid adenoma. A review of the literature of PHPT in adolescents was performed, focusing on etiology, clinical presentation, preoperative localization methods, pathology, and treatment.
RESULTS: The patient was successfully treated with surgery and was followed up for 5 years with no signs or symptoms of hyperparathyroidism. By reviewing the literature, only seven cases of PHPT associated with ectopic parathyroid lesions in adolescents have been reported. Parathyroidectomy is the only known curative treatment. Accurate preoperative localization of the target lesion is critical.
CONCLUSIONS: This study should raise awareness of the diagnosis and treatment of PHPT due to ectopic parathyroid adenoma/carcinoma in adolescents.

Entities:  

Keywords:  Adolescent; Ectopic parathyroid gland; Parathyroid hormone; Parathyroidectomy; Primary hyperparathyroidism

Year:  2019        PMID: 30805889     DOI: 10.1007/s12020-019-01875-3

Source DB:  PubMed          Journal:  Endocrine        ISSN: 1355-008X            Impact factor:   3.633


  30 in total

Review 1.  Clinical update: sporadic primary hyperparathyroidism.

Authors:  Antonio Sitges-Serra; Anders Bergenfelz
Journal:  Lancet       Date:  2007-08-11       Impact factor: 79.321

Review 2.  Fusion imaging for parathyroid localization in primary hyperparathyroidism.

Authors:  Daniel S Levine; Sam M Wiseman
Journal:  Expert Rev Anticancer Ther       Date:  2010-03       Impact factor: 4.512

Review 3.  Primary hyperparathyroidism in the 1990s. Choice of surgical procedures for this disease.

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Journal:  Ann Surg       Date:  1992-04       Impact factor: 12.969

4.  A 10-year retrospective study of primary hyperparathyroidism in children.

Authors:  C-C Li; C Yang; S Wang; J Zhang; X-R Kong; J Ouyang
Journal:  Exp Clin Endocrinol Diabetes       Date:  2012-02-10       Impact factor: 2.949

Review 5.  Hyperparathyroidism.

Authors:  William D Fraser
Journal:  Lancet       Date:  2009-07-11       Impact factor: 79.321

6.  Radio-guided thoracoscopic surgery with (99m)Tc-methoxy-isobutylisonitrile for treating an ectopic mediastinal parathyroid adenoma in an adolescent girl.

Authors:  Yoshihiro Minamiya; Hajime Saito; Manabu Ito; Satoru Motoyama; Yoshihisa Katayose; Jun-ichi Ogawa
Journal:  Gen Thorac Cardiovasc Surg       Date:  2009-12

7.  The fallen one: the inferior parathyroid gland that descends into the mediastinum.

Authors:  Glenda G Callender; Elizabeth G Grubbs; Thinh Vu; Wayne L Hofstetter; Jason B Fleming; Katherine L Woodburn; Jeffrey E Lee; Douglas B Evans; Nancy D Perrier
Journal:  J Am Coll Surg       Date:  2009-05       Impact factor: 6.113

Review 8.  Mediastinal parathyroid adenomas and their surgical implications.

Authors:  Jesse Hu; K Y Ngiam; R Parameswaran
Journal:  Ann R Coll Surg Engl       Date:  2015-05       Impact factor: 1.891

Review 9.  Primary hyperparathyroidism.

Authors:  Marcella D Walker; Shonni J Silverberg
Journal:  Nat Rev Endocrinol       Date:  2017-09-08       Impact factor: 43.330

10.  Ectopic mediastinal parathyroid adenoma localized with four-dimensional CT: a case report.

Authors:  Islam A Shehata Elhelf; Jack C Kademian; Toshio Moritani; Aristides E Capizzano; Bruno Policeni; Joan Maley
Journal:  Radiol Case Rep       Date:  2017-02-20
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  5 in total

1.  Multiple endocrine neoplasia type 1 with ectopic parathyroid adenoma.

Authors:  Qiaorui Liu; Liming Wu; Xulei Zheng; Cong Ma; Risu Na; Ling Qiu; Zhiwen Liu; Liyan Liao
Journal:  Arch Med Sci       Date:  2022-04-14       Impact factor: 3.707

2.  Ectopic Parathyroid Adenoma in an 11-Year-Old Girl: Case Report and Literature Review.

Authors:  Myrto Eleni Flokas; Gulnigor Ganieva; Amanda Grieco; Levon Agdere
Journal:  AACE Clin Case Rep       Date:  2020-11-28

Review 3.   Misdiagnosis of brown tumour caused by primary hyperparathyroidism: a case report with literature review.

Authors:  Yanchun Zhong; Yuxi Huang; Jiaquan Luo; Yongjun Ye
Journal:  BMC Endocr Disord       Date:  2022-03-14       Impact factor: 2.763

4.  Undescended retropharyngeal parathyroid adenoma with adjacent thymic tissue in a 13-year-old boy with primary hyperparathyroidism.

Authors:  Anthony M Kordahi; Ron S Newfield; Stephen W Bickler; Jun Q Mo; Paritosh C Khanna; Julie Bykowski; Michael Bouvet
Journal:  Oxf Med Case Reports       Date:  2019-12-31

Review 5.  Severe bone disease caused by primary hyperparathyroidism: a case report and review of the literature.

Authors:  Yu Wang; Jie Liu
Journal:  J Int Med Res       Date:  2020-10       Impact factor: 1.671

  5 in total

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