Literature DB >> 3080331

Primary structure of the alpha-subunit of bovine adenylate cyclase-stimulating G-protein deduced from the cDNA sequence.

T Nukada, T Tanabe, H Takahashi, M Noda, T Hirose, S Inayama, S Numa.   

Abstract

The primary structure of the alpha-subunit of the adenylate cyclase-stimulating G-protein (Gs) has been deduced from the nucleotide sequence of cloned DNA complementary to the bovine cerebral mRNA encoding the polypeptide. Comparison of the amino acid sequences of the alpha-subunits of Gs and transducin reveals that some of the highly conserved regions show sequence homology with elongation factor-Tu and ras p21 proteins and correspond to functional regions of guanine nucleotide-binding proteins.

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Year:  1986        PMID： 3080331     DOI： 10.1016/0014-5793(86)80164-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  13 in total

1.  Phylogeny and evolutionary rates of G protein alpha subunit genes.

Authors:  S Yokoyama; W T Starmer
Journal:  J Mol Evol       Date:  1992-09       Impact factor: 2.395

2.  Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers.

Authors:  Lutz Birnbaumer
Journal:  Biochim Biophys Acta       Date:  2006-12-15

3.  Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

Authors:  H Itoh; T Kozasa; S Nagata; S Nakamura; T Katada; M Ui; S Iwai; E Ohtsuka; H Kawasaki; K Suzuki
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

4.  Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

Authors:  K P Van Meurs; C W Angus; S Lavu; H F Kung; S K Czarnecki; J Moss; M Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

5.  Identification of the probable site of choleragen-catalyzed ADP-ribosylation in a Go alpha-like protein based on cDNA sequence.

Authors:  C W Angus; K P Van Meurs; S C Tsai; R Adamik; M C Miedel; Y C Pan; H F Kung; J Moss; M Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

6.  Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.

Authors:  T Michel; J W Winslow; J A Smith; J G Seidman; E J Neer
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

7.  Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

Authors:  M Matsuoka; H Itoh; T Kozasa; Y Kaziro
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

8.  G protein-mediated inhibition of phosphoinositide metabolism evoked by metabotropic glutamate receptors in frog oocytes.

Authors:  K Nakamura; T Nukada; T Haga; H Sugiyama
Journal:  J Physiol       Date:  1994-01-01       Impact factor: 5.182

9.  Human cDNA clones for an alpha subunit of Gi signal-transduction protein.

Authors:  P Bray; A Carter; V Guo; C Puckett; J Kamholz; A Spiegel; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

10.  Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the alpha subunit of mammalian G proteins.

Authors:  M Nakafuku; H Itoh; S Nakamura; Y Kaziro
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205
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