Literature DB >> 30803263

Human-relevant preclinical in vitro models for studying hepatobiliary development and liver diseases using induced pluripotent stem cells.

Pooja Chaudhari1,2, Lipeng Tian1, Zhaohui Ye3, Yoon-Young Jang1,2,3,4.   

Abstract

IMPACT STATEMENT: In this review, we address the potential of human-induced pluripotent stem cell-based hepatobiliary differentiation technology as a means to study human liver development and cell fate determination, and to model liver diseases in an effort to develop a new human-relevant preclinical platform for drug development.

Entities:  

Keywords:  Human-induced pluripotent stem cell; YAP; hepatobiliary development; liver disease

Mesh：

Substances：

Year:  2019        PMID： 30803263      PMCID： PMC6552401          DOI： 10.1177/1535370219834895

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN： 1535-3699


  58 in total

Review 1.  Concordance of the toxicity of pharmaceuticals in humans and in animals.

Authors:  H Olson; G Betton; D Robinson; K Thomas; A Monro; G Kolaja; P Lilly; J Sanders; G Sipes; W Bracken; M Dorato; K Van Deun; P Smith; B Berger; A Heller
Journal:  Regul Toxicol Pharmacol       Date:  2000-08       Impact factor: 3.271

2.  An identification of novel therapy for human hepatocellular carcinoma by using human induced pluripotent stem cells.

Authors:  Hisashi Moriguchi; Raymond T Chung; Chifumi Sato
Journal:  Hepatology       Date:  2010-03       Impact factor: 17.425

3.  Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans.

Authors:  Alessia Omenetti; Alessandro Porrello; Youngmi Jung; Liu Yang; Yury Popov; Steve S Choi; Rafal P Witek; Gianfranco Alpini; Juliet Venter; Hendrika M Vandongen; Wing-Kin Syn; Gianluca Svegliati Baroni; Antonio Benedetti; Detlef Schuppan; Anna Mae Diehl
Journal:  J Clin Invest       Date:  2008-10       Impact factor: 14.808

Review 4.  Drug-induced liver injury.

Authors:  Gebran Abboud; Neil Kaplowitz
Journal:  Drug Saf       Date:  2007       Impact factor: 5.606

5.  Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.

Authors:  Alessia Omenetti; Liu Yang; Yin-Xiong Li; Shannon J McCall; Youngmi Jung; Jason K Sicklick; Jiawen Huang; Steve Choi; Ayako Suzuki; Anna Mae Diehl
Journal:  Lab Invest       Date:  2007-03-05       Impact factor: 5.662

6.  Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.

Authors:  Youngmi Jung; Shannon J McCall; Yin-Xiong Li; Anna Mae Diehl
Journal:  Hepatology       Date:  2007-05       Impact factor: 17.425

7.  The hedgehog pathway regulates remodelling responses to biliary obstruction in rats.

Authors:  A Omenetti; Y Popov; Y Jung; S S Choi; R P Witek; L Yang; K D Brown; D Schuppan; A M Diehl
Journal:  Gut       Date:  2008-03-28       Impact factor: 23.059

8.  Characterization of time-related changes after experimental bile duct ligation.

Authors:  P Georgiev; W Jochum; S Heinrich; J H Jang; A Nocito; F Dahm; P-A Clavien
Journal:  Br J Surg       Date:  2008-05       Impact factor: 6.939

Review 9.  Review of hepatocyte transplantation.

Authors:  Masahiro Ito; Hideo Nagata; Shuichi Miyakawa; Ira J Fox
Journal:  J Hepatobiliary Pancreat Surg       Date:  2008-12-27

10.  Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders.

Authors:  Zhaohui Ye; Huichun Zhan; Prashant Mali; Sarah Dowey; Donna M Williams; Yoon-Young Jang; Chi V Dang; Jerry L Spivak; Alison R Moliterno; Linzhao Cheng
Journal:  Blood       Date:  2009-10-01       Impact factor: 22.113
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  1 in total

1.  A comparison of hepato-cellular in vitro platforms to study CYP3A4 induction.

Authors:  Beyza Bulutoglu; Camilo Rey-Bedón; Safak Mert; Lipeng Tian; Yoon-Young Jang; Martin L Yarmush; O Berk Usta
Journal:  PLoS One       Date:  2020-02-27       Impact factor: 3.240
  1 in total

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