| Literature DB >> 30801075 |
Barbara E Souza1, Svemir Rudić, Kirill Titov, Arun S Babal, James D Taylor, Jin-Chong Tan.
Abstract
A facile mechanochemical method was employed to accomplish one-pot encapsulation of anti-cancer drug 5-fluorouracil (5-FU as guest) in a metal-organic framework (HKUST-1 as host). Vibrational spectroscopy via inelastic neutron scattering was applied to probe guest-host interactions arising from nanoscale confinement. We compare 5-FU@HKUST-1 derived from in situ and ex situ encapsulation.Entities:
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Year: 2019 PMID： 30801075 DOI： 10.1039/c8cc10089f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222