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Literature DB >> 30797598

Electronic Health Records Are the Next Frontier for the Genetics of Substance Use Disorders.

Sandra Sanchez-Roige¹, Abraham A Palmer².

Abstract

Compared with other psychiatric disorders of similar heritabilities, the progress of substance use disorders (SUD) genetics has been slow. With the growing availability of large-scale biobanks with extensive phenotypes from electronic health records (EHR) and genotypes across millions of individuals, this platform is the next tool to accelerate SUD genetics research.

Entities: Chemical Disease Gene Species

Keywords: biobanks; electronic health records; genetics; substance use disorders

Mesh：

Year: 2019 PMID： 30797598 PMCID： PMC6984003 DOI： 10.1016/j.tig.2019.01.007

Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639

11 in total

1. Combining billing codes, clinical notes, and medications from electronic health records provides superior phenotyping performance.

Authors: Wei-Qi Wei; Pedro L Teixeira; Huan Mo; Robert M Cronin; Jeremy L Warner; Joshua C Denny
Journal: J Am Med Inform Assoc Date: 2015-09-02 Impact factor: 4.497

2. An analysis of free-text alcohol use documentation in the electronic health record: early findings and implications.

Authors: Es Chen; M Garcia-Webb
Journal: Appl Clin Inform Date: 2014-04-16 Impact factor: 2.342

3. Sensitivity of Claims-Based Algorithms to Ascertain Smoking Status More Than Doubled with Meaningful Use.

Authors: Jinhai Huo; Ming Yang; Ya-Chen Tina Shih
Journal: Value Health Date: 2017-10-18 Impact factor: 5.725

Review 4. Human Genetics of Addiction: New Insights and Future Directions.

Authors: Dana B Hancock; Christina A Markunas; Laura J Bierut; Eric O Johnson
Journal: Curr Psychiatry Rep Date: 2018-03-05 Impact factor: 5.285

Review 5. The use of electronic health records for psychiatric phenotyping and genomics.

Authors: Jordan W Smoller
Journal: Am J Med Genet B Neuropsychiatr Genet Date: 2017-05-30 Impact factor: 3.568

6. TextHunter--A User Friendly Tool for Extracting Generic Concepts from Free Text in Clinical Research.

Authors: Richard G Jackson MSc; Michael Ball; Rashmi Patel; Richard D Hayes; Richard J B Dobson; Robert Stewart
Journal: AMIA Annu Symp Proc Date: 2014-11-14

7. Validation of electronic health record phenotyping of bipolar disorder cases and controls.

Authors: Victor M Castro; Jessica Minnier; Shawn N Murphy; Isaac Kohane; Susanne E Churchill; Vivian Gainer; Tianxi Cai; Alison G Hoffnagle; Yael Dai; Stefanie Block; Sydney R Weill; Mireya Nadal-Vicens; Alisha R Pollastri; J Niels Rosenquist; Sergey Goryachev; Dost Ongur; Pamela Sklar; Roy H Perlis; Jordan W Smoller
Journal: Am J Psychiatry Date: 2014-12-12 Impact factor: 18.112

8. Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records.

Authors: Chia-Yen Chen; Phil H Lee; Victor M Castro; Jessica Minnier; Alexander W Charney; Eli A Stahl; Douglas M Ruderfer; Shawn N Murphy; Vivian Gainer; Tianxi Cai; Ian Jones; Carlos N Pato; Michele T Pato; Mikael Landén; Pamela Sklar; Roy H Perlis; Jordan W Smoller
Journal: Transl Psychiatry Date: 2018-04-18 Impact factor: 6.222

Review 9. Automatable algorithms to identify nonmedical opioid use using electronic data: a systematic review.

Authors: Chelsea Canan; Jennifer M Polinski; G Caleb Alexander; Mary K Kowal; Troyen A Brennan; William H Shrank
Journal: J Am Med Inform Assoc Date: 2017-11-01 Impact factor: 4.497

10. Development of phenotype algorithms using electronic medical records and incorporating natural language processing.

Authors: Katherine P Liao; Tianxi Cai; Guergana K Savova; Shawn N Murphy; Elizabeth W Karlson; Ashwin N Ananthakrishnan; Vivian S Gainer; Stanley Y Shaw; Zongqi Xia; Peter Szolovits; Susanne Churchill; Isaac Kohane
Journal: BMJ Date: 2015-04-24

3 in total

Review 1. Recent Efforts to Dissect the Genetic Basis of Alcohol Use and Abuse.

Authors: Sandra Sanchez-Roige; Abraham A Palmer; Toni-Kim Clarke
Journal: Biol Psychiatry Date: 2019-09-25 Impact factor: 13.382

2. On the path towards personalized medicine: Implications of pharmacogenetic studies of alcohol use disorder medications.

Authors: Steven J Nieto; Erica N Grodin; Lara A Ray
Journal: Expert Rev Precis Med Drug Dev Date: 2020-02-10

Review 3. Emerging phenotyping strategies will advance our understanding of psychiatric genetics.

Authors: Sandra Sanchez-Roige; Abraham A Palmer
Journal: Nat Neurosci Date: 2020-03-30 Impact factor: 28.771

3 in total