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Literature DB >> 3079685

Use of an IgA-depleted intravenous immunoglobulin in a patient with an anti-IgA antibody.

C Cunningham-Rundles, S Wong, J Björkander, L A Hanson.

Abstract

In this report we describe the use of an IgA-depleted preparation of intravenous gamma-globulin in a patient with hypogammaglobulinemia and an anti-IgA antibody. An IgA containing intravenous gamma-globulin had previously produced anaphylactoid reactions, immune complex formation, and complement activation. The patient has had no reactions to the IgA-depleted preparation after 18 months of treatment; immune complex formation and complement activation have not been demonstrated, and the titer of antibody to IgA has diminished.

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Year: 1986 PMID： 3079685 DOI： 10.1016/0090-1229(86)90133-9

Source DB: PubMed Journal: Clin Immunol Immunopathol ISSN： 0090-1229

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Cited

7 in total

1. IgG anti-IgA subclasses in common variable immunodeficiency and association with severe adverse reactions to intravenous immunoglobulin therapy.

Authors: R de Albuquerque Campos; M N Sato; A J da Silva Duarte
Journal: J Clin Immunol Date: 2000-01 Impact factor: 8.317

7. Anaphylaxis to IGIV in immunoglobulin-naïve common variable immunodeficiency patient in the absence of IgG anti-IgA antibodies: successful administration of low IgA-containing immunoglobulin.

Authors: Asal Gharib; Caroline Caperton; Sudhir Gupta
Journal: Allergy Asthma Clin Immunol Date: 2016-05-17 Impact factor: 3.406

7 in total

Use of an IgA-depleted intravenous immunoglobulin in a patient with an anti-IgA antibody.

1. IgG anti-IgA subclasses in common variable immunodeficiency and association with severe adverse reactions to intravenous immunoglobulin therapy.

2. Association of anti-IgA antibodies with adverse reactions to γ-globulin infusion.

3. Anti-IgA antibodies in IgA-deficient children.

4. Long-term use of IgA-depleted intravenous immunoglobulin in immunodeficient subjects with anti-IgA antibodies.

Review 5. Common variable immunodeficiency: etiological and treatment issues.

6. Induction of unresponsiveness against IgA in IgA-deficient patients on subcutaneous immunoglobulin infusion therapy.

7. Anaphylaxis to IGIV in immunoglobulin-naïve common variable immunodeficiency patient in the absence of IgG anti-IgA antibodies: successful administration of low IgA-containing immunoglobulin.