Literature DB >> 3079583

Antibacterial activity of Ro 17-2301 and other antimicrobial agents against cefotaxime-resistant aerobic gram-negative bacilli.

C A Benson, F E Walton, G M Trenholme.   

Abstract

The in vitro activity of Ro 17-2301 was determined and compared with those of aztreonam, ceftazidime, amikacin, and piperacillin against 141 cefotaxime-resistant gram-negative bacilli. Ro 17-2301 was bactericidal, and its activity against the majority of these organisms was equal or superior to those of ceftazidime, aztreonam, and piperacillin. An inoculum effect of Ro 17-2301 and aztreonam for many Pseudomonas aeruginosa and Enterobacter spp. isolates was demonstrated.

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Year:  1986        PMID： 3079583      PMCID： PMC180383          DOI： 10.1128/AAC.29.1.155

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

1.  In vitro activities of Ro 17-2301 and aztreonam compared with those of other new beta-lactam antibiotics against clinical isolates of Pseudomonas aeruginosa.

Authors:  W W Ng; P Y Chau; Y K Leung; D M Livermore
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

2.  SQ 26,776: in-vitro antibacterial activity and susceptibility to beta-lactamases.

Authors:  I Phillips; A King; K Shannon; C Warren
Journal:  J Antimicrob Chemother       Date:  1981-12       Impact factor: 5.790

3.  Monobactams--monocyclic beta-lactam antibiotics produced by bacteria.

Authors:  R B Sykes; D P Bonner; K Bush; N H Georgopapadakou; J S Wells
Journal:  J Antimicrob Chemother       Date:  1981-12       Impact factor: 5.790

4.  SQ 26,776, a novel beta-lactam: an in-vitro comparison with other antimicrobial agents.

Authors:  R Wise; J M Andrews; J Hancox
Journal:  J Antimicrob Chemother       Date:  1981-12       Impact factor: 5.790

5.  Inoculum effect of new beta-lactam antibiotics on Pseudomonas aeruginosa.

Authors:  R H Eng; S M Smith; C Cherubin
Journal:  Antimicrob Agents Chemother       Date:  1984-07       Impact factor: 5.191

6.  Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria.

Authors:  R B Sykes; D P Bonner; K Bush; N H Georgopapadakou
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191

7.  The in-vitro activity of Ro 17-2301, a new monobactam, compared with other antimicrobial agents.

Authors:  R Wise; J M Andrews; L J Piddock
Journal:  J Antimicrob Chemother       Date:  1985-02       Impact factor: 5.790

8.  Pharmacokinetics and tissue penetration of carumonam, a new synthetic monobactam.

Authors:  C A McNulty; G M Garden; J Ashby; R Wise
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191
  8 in total
  3 in total

1.  Comparative in vitro activity of A-56268 (TE-031) against gram-positive and gram-negative bacteria and Chlamydia trachomatis.

Authors:  C Benson; J Segreti; H Kessler; D Hines; L Goodman; R Kaplan; G Trenholme
Journal:  Eur J Clin Microbiol       Date:  1987-04       Impact factor: 3.267

2.  In vitro susceptibility of Citrobacter species to various antimicrobial agents.

Authors:  G Samonis; D H Ho; G F Gooch; K V Rolston; G P Bodey
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

3.  Carumonam enhances reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5.

Authors:  B P Overbeek; J F Schellekens; W Lippe; B A Dekker; J Verhoef
Journal:  J Clin Microbiol       Date:  1987-06       Impact factor: 5.948
  3 in total

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