Literature DB >> 30794063

Intratympanic steroid therapy for refractory sudden sensory hearing loss: a 12-year experience with the Silverstein catheter.

France Vanwijck1, Florence Rogister1, Sébastien Pierre Barriat1, Severine Camby1, Philippe Lefebvre1.   

Abstract

BACKGROUND: Sudden sensorineural hearing loss (SSNHL) is commonly encountered in clinical practice. AIM/
OBJECTIVE: Determine if local administration of corticosteroids to the inner ear can improve hearing and speech intelligibility after the failure of conventional treatment for SSNHL loss when administered for 10 days after the onset of the hearing loss in a large cohort of 77 patients.
MATERIALS AND METHODS: A Silverstein MicroWick™ was placed under local anesthesia and endoscopic control in the round window niche, allowing self-administration of methylprednisolone twice daily for four weeks.
RESULTS: An improvement of the pure tone average was shown in 31% of patients. Speech intelligibility improved significantly in 55% of the total cohort and in 34% of the population with a stable pure tone average. Among the 77 patients, 22% used a hearing aid. Only 14% of the patients were hearing-aid users in the group with an improvement in speech intelligibility as opposed to 31% in the failure group. CONCLUSION AND SIGNIFICANCE: Local administration of steroids to the inner ear through the round window route improves hearing and speech intelligibility in patients after failure of conventional therapy. The use of a hearing aid was reduced by 50% when speech intelligibility was improved.

Entities:  

Keywords:  Idiopathic sudden sensorineural hearing loss; intratympanic therapy; steroid therapy

Mesh:

Substances:

Year:  2019        PMID: 30794063     DOI: 10.1080/00016489.2018.1532107

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  4 in total

1.  Comparing the Efficiencies of Hyperbaric Oxygen Therapy and Intratympanic Steroid Treatment for Sudden Hearing Loss.

Authors:  Erkan Eski; Seda Babakurban; Serkan Yılmaz; Cüneyt Yılmazer; Alper Nabi Erkan; Fatma Çaylaklı; İsmail Yılmaz
Journal:  J Int Adv Otol       Date:  2020-08       Impact factor: 1.017

Review 2.  Application of New Materials in Auditory Disease Treatment.

Authors:  Ming Li; Yurong Mu; Hua Cai; Han Wu; Yanyan Ding
Journal:  Front Cell Neurosci       Date:  2022-01-31       Impact factor: 5.505

3.  Intratympanic Steroid for the Management of Sudden Hearing Loss: Introduction of a Tapering Method.

Authors:  Mohsen Rajati; Mohammad Mehdi Ghasemi; Mohammad-Reza Sharifian; Navid Nourizadeh; Razieh Yousefi; Masoumeh Hosseinpoor
Journal:  Iran J Otorhinolaryngol       Date:  2022-01

4.  Efficacy of Ginkgo biloba Extract Combined with Hormones in the Treatment of Sudden Deafness and Its Effect on the Reactivity of Peripheral Blood T Cell Subsets.

Authors:  Zhenhua Zhu; Qi Wu; Ge Hu; Xianwen Wang; Wei Chang; Ji Bin; Weili Yang
Journal:  Comput Math Methods Med       Date:  2022-09-26       Impact factor: 2.809

  4 in total

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