Literature DB >> 30793199

A primer in genomics for social and behavioral investigators.

Erin Turbitt1,2, Barbara B Biesecker3.   

Abstract

Genomics is being increasingly utilized in medical research and health care. Countless opportunities exist for social and behavioral scientists to answer novel and important research questions. Evidence that will be produced from such enquiries can help ensure appropriate use of genomic information and realize the potential of genomics to improve patient care and medical outcomes. Here, we provide an accessible overview of different types of genetic and genomic tests and the resulting information produced. There are important nuances that distinguish genetic from genomic tests and different information that each yield. We outline key examples where social and behavioral scientists have made an impact in this field, and opportunities for future research. The intention of this primer is to introduce or clarify genomics concepts to social and behavioral scientists, summarize prior research and outline future research directions. The time is ripe for social and behavioral scientists to engage in genomics and make important contributions to improve clinical and community translation of genomic discoveries. © Society of Behavioral Medicine 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Behavioral sciences; Genomics; Social sciences; Translational research

Mesh:

Year:  2020        PMID: 30793199      PMCID: PMC7237540          DOI: 10.1093/tbm/ibz018

Source DB:  PubMed          Journal:  Transl Behav Med        ISSN: 1613-9860            Impact factor:   3.046


  41 in total

1.  Screening adherence and cancer risk perceptions in colorectal cancer survivors with Lynch-like syndrome.

Authors:  L H Katz; A M Burton-Chase; S Advani; B Fellman; K M Polivka; Y Yuan; P M Lynch; S K Peterson
Journal:  Clin Genet       Date:  2015-09-14       Impact factor: 4.438

2.  Genetic test reporting enhances understanding of risk information and acceptance of prevention recommendations compared to family history-based counseling alone.

Authors:  Jennifer M Taber; Lisa G Aspinwall; Tammy K Stump; Wendy Kohlmann; Marjan Champine; Sancy A Leachman
Journal:  J Behav Med       Date:  2015-07-16

3.  Preferences for results from genomic microarrays: comparing parents and health care providers.

Authors:  E Turbitt; J L Halliday; D J Amor; S A Metcalfe
Journal:  Clin Genet       Date:  2014-04-29       Impact factor: 4.438

4.  National Estimates of Genetic Testing in Women With a History of Breast or Ovarian Cancer.

Authors:  Christopher P Childers; Kimberly K Childers; Melinda Maggard-Gibbons; James Macinko
Journal:  J Clin Oncol       Date:  2017-08-18       Impact factor: 44.544

5.  Do women change their breast cancer mammogram screening behaviour after BRCA1/2 testing?

Authors:  Geneviève Larouche; Jocelyne Chiquette; Sylvie Pelletier; Jacques Simard; Michel Dorval
Journal:  Fam Cancer       Date:  2017-01       Impact factor: 2.375

6.  Molecular findings among patients referred for clinical whole-exome sequencing.

Authors:  Yaping Yang; Donna M Muzny; Fan Xia; Zhiyv Niu; Richard Person; Yan Ding; Patricia Ward; Alicia Braxton; Min Wang; Christian Buhay; Narayanan Veeraraghavan; Alicia Hawes; Theodore Chiang; Magalie Leduc; Joke Beuten; Jing Zhang; Weimin He; Jennifer Scull; Alecia Willis; Megan Landsverk; William J Craigen; Mir Reza Bekheirnia; Asbjorg Stray-Pedersen; Pengfei Liu; Shu Wen; Wendy Alcaraz; Hong Cui; Magdalena Walkiewicz; Jeffrey Reid; Matthew Bainbridge; Ankita Patel; Eric Boerwinkle; Arthur L Beaudet; James R Lupski; Sharon E Plon; Richard A Gibbs; Christine M Eng
Journal:  JAMA       Date:  2014-11-12       Impact factor: 56.272

7.  Clinical exome sequencing for genetic identification of rare Mendelian disorders.

Authors:  Hane Lee; Joshua L Deignan; Naghmeh Dorrani; Samuel P Strom; Sibel Kantarci; Fabiola Quintero-Rivera; Kingshuk Das; Traci Toy; Bret Harry; Michael Yourshaw; Michelle Fox; Brent L Fogel; Julian A Martinez-Agosto; Derek A Wong; Vivian Y Chang; Perry B Shieh; Christina G S Palmer; Katrina M Dipple; Wayne W Grody; Eric Vilain; Stanley F Nelson
Journal:  JAMA       Date:  2014-11-12       Impact factor: 56.272

8.  What can interest tell us about uptake of genetic testing? Intention and behavior amongst smokers related to patients with lung cancer.

Authors:  S C Sanderson; S C O'Neill; L A Bastian; G Bepler; C M McBride
Journal:  Public Health Genomics       Date:  2009-06-29       Impact factor: 2.000

9.  Patients' understanding of and responses to multiplex genetic susceptibility test results.

Authors:  Kimberly A Kaphingst; Colleen M McBride; Christopher Wade; Sharon Hensley Alford; Robert Reid; Eric Larson; Andreas D Baxevanis; Lawrence C Brody
Journal:  Genet Med       Date:  2012-07       Impact factor: 8.822

10.  Returning incidental findings from genetic research to children: views of parents of children affected by rare diseases.

Authors:  Erika Kleiderman; Bartha Maria Knoppers; Conrad V Fernandez; Kym M Boycott; Gail Ouellette; Durhane Wong-Rieger; Shelin Adam; Julie Richer; Denise Avard
Journal:  J Med Ethics       Date:  2013-12-19       Impact factor: 2.903

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  1 in total

1.  Advancing precision public health using human genomics: examples from the field and future research opportunities.

Authors:  Megan C Roberts; Alison E Fohner; Latrice Landry; Dana Lee Olstad; Amelia K Smit; Erin Turbitt; Caitlin G Allen
Journal:  Genome Med       Date:  2021-06-01       Impact factor: 11.117

  1 in total

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