Bertrand Prunet1,2, Jérémy Bourenne3, Jean-Stéphane David4, Pierre Bouzat5, Mathieu Boutonnet6, Pierre-Yves Cordier7, Pierre Renaudin8, Eric Meaudre1, Pierre Michelet2,3. 1. Department of Critical Care, Sainte Anne Military Teaching Hospital, Toulon, France. 2. UMR MD2, Aix-Marseille University, School of Medicine, Marseille, France. 3. Department of Critical Care, Timone University Hospital, Marseille, France. 4. Department of Critical Care, Lyon-Sud University Hospital, Pierre-Bénite, France. 5. Department of Critical Care, Grenoble University Hospital, France. 6. Department of Critical Care, Percy Military Teaching Hospital, Clamart, France. 7. Department of Critical Care, Laveran Military Teaching Hospital, Marseille, France. 8. Department of Public Health, Timone University Hospital, Marseille, France.
Abstract
INTRODUCTION: This study investigated invasive mechanical ventilation modalities used in severe blunt chest trauma patients with pulmonary contusion. Occurrence, risk factors, and outcomes of early onset acute respiratory distress syndrome were also evaluated. METHODS: We performed a retrospective multicenter observational study including 115 adult patients hospitalized in six level 1 trauma intensive care units between April and September of 2014. Independent predictors of early onset acute respiratory distress syndrome were determined by multiple logistic regression analysis based on clinical characteristics and initial management. RESULTS: Protective ventilation principles were highly implemented, even prophylactically before acute respiratory distress syndrome occurrence. Early onset acute respiratory distress syndrome appeared to be associated with lung contusion of >20% of total lung volume and early onset pneumonia. CONCLUSIONS: Predictors of early onset acute respiratory distress syndrome could help with identifying high-risk populations, potentially improving case management through specific protocol development for these patients.
INTRODUCTION: This study investigated invasive mechanical ventilation modalities used in severe blunt chest trauma patients with pulmonary contusion. Occurrence, risk factors, and outcomes of early onset acute respiratory distress syndrome were also evaluated. METHODS: We performed a retrospective multicenter observational study including 115 adult patients hospitalized in six level 1 trauma intensive care units between April and September of 2014. Independent predictors of early onset acute respiratory distress syndrome were determined by multiple logistic regression analysis based on clinical characteristics and initial management. RESULTS: Protective ventilation principles were highly implemented, even prophylactically before acute respiratory distress syndrome occurrence. Early onset acute respiratory distress syndrome appeared to be associated with lung contusion of >20% of total lung volume and early onset pneumonia. CONCLUSIONS: Predictors of early onset acute respiratory distress syndrome could help with identifying high-risk populations, potentially improving case management through specific protocol development for these patients.
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