| Literature DB >> 30790148 |
Miaomiao Nie1,2,3, Xungang Tan1,2, Yunliang Lu1,2, Zhihao Wu1,2, Jun Li1,2, Dongdong Xu4, Peijun Zhang1,2, Feng You5,6,7.
Abstract
The aim of this study is to understand fish cold-tolerant mechanism. We analyzed the transcriptional reactions to the cold condition in turbot Scophthalmus maximus by using RNA-seq and microRNA (miRNA)-seq. Meio-gynogenetic diploid turbots were treated at 0 °C to distinguish the cold-tolerant (CT) and cold-sensitive (CS) groups. The results showed that there were quite different responses at both mRNA and miRNA levels, with more up-regulated mRNAs (1069 vs. 194) and less down-regulated miRNAs (4 vs. 1) in CT versus CS relative to the control group. The network of miRNA-transcription factor-mRNA, regulating turbot different response to cold stress, was constructed, which involved in cell cycle, component of cell membrane, signal transduction, and circadian rhythm pathways. The above information demonstrates mechanisms by which cold tolerance is increased in fish.Entities:
Keywords: Cold tolerance; Scophthalmus maximus; Transcription; Transcription factor; microRNA
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Year: 2019 PMID： 30790148 DOI： 10.1007/s10695-019-00611-y
Source DB: PubMed Journal: Fish Physiol Biochem ISSN： 0920-1742 Impact factor: 2.794