Literature DB >> 30787026

Acute adrenal failure: a potentially fatal consequence of an adulterated herbal remedy.

Harminder Sensi1, Harit Buch2, Loretta Ford3, Rousseau Gama3.   

Abstract

Herbal remedies adulterated with glucocorticoids can cause Cushing's syndrome. We report a severe presentation of a 'herbal remedy' adulterated with glucocorticoids; causing a potentially fatal adrenal crisis precipitated by acute illness. Investigations were consistent with adrenal suppression and confirmed, after tablet analysis, to be due to a 'herbal remedy' containing synthetic betamethasone/dexamethasone. This case highlights the need for clinical vigilance and patient education about the potential risks associated with the use of unlicensed treatments and the role of tablet analysis in routine biochemistry. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  adrenal disorders; endocrine system

Mesh:

Substances:

Year:  2019        PMID: 30787026      PMCID: PMC6388792          DOI: 10.1136/bcr-2018-228443

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  18 in total

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5.  Exogenous Cushing's syndrome due to a Chinese herbalist's prescription of ointment containing dexamethasone.

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Journal:  BMJ Case Rep       Date:  2017-04-20

6.  Herbal medicine research and global health: an ethical analysis.

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Journal:  Eur J Endocrinol       Date:  2008-11-14       Impact factor: 6.664

8.  Cushing in a Leaf: Endocrine Disruption From a Natural Remedy.

Authors:  Chiara Martini; Eva Zanchetta; Mauro Di Ruvo; Alessandro Nalesso; Marialberta Battocchio; Erica Gentilin; Ettore Degli Uberti; Roberto Vettor; Maria Chiara Zatelli
Journal:  J Clin Endocrinol Metab       Date:  2016-05-24       Impact factor: 5.958

9.  Adrenal suppression following herbal remedy for rheumatoid arthritis.

Authors:  Balasekar Premkumar; Muppavarapu Srinivasa Murthy; Karuppasamy Rajagopal; Vadivelmurugan Nagasubramani Nagaprabu; Sree Madhuri Ponugupati
Journal:  J Pharmacol Pharmacother       Date:  2015 Apr-Jun

10.  South African medicinal plant extracts active against influenza A virus.

Authors:  Parvaneh Mehrbod; Muna A Abdalla; Emmanuel M Njoya; Aroke S Ahmed; Fatemeh Fotouhi; Behrokh Farahmand; Dorcas A Gado; Mansoureh Tabatabaian; Olubunmi G Fasanmi; Jacobus N Eloff; Lyndy J McGaw; Folorunso O Fasina
Journal:  BMC Complement Altern Med       Date:  2018-03-27       Impact factor: 3.659

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