Literature DB >> 30786971

Regulating gabapentin as a drug of abuse: A survey study of Kentucky community pharmacists.

James Blackmer, Eric Lindahl, Audra Strahl, Aric Schadler, Patricia R Freeman.   

Abstract

OBJECTIVES: As the number of gabapentin prescriptions has increased, so have reports of its misuse and diversion. This trend has led some states to closer monitoring of gabapentin dispensing through prescription drug monitoring programs (PDMPs). The objective of this study was to collect and analyze Kentucky community pharmacists' perceptions of gabapentin misuse and diversion, and their support or opposition to regulatory efforts to reclassify the drug as a controlled substance (CS).
METHODS: Responses were collected using an online survey sent by e-mail to all pharmacists practicing in Kentucky in August 2016. The survey collected basic demographic characteristics and pharmacists' experience with gabapentin dispensing. Descriptive statistics were calculated using question response frequencies. Pearson's chi-squared statistics were calculated to examine the distribution of support for gabapentin as a CS in Kentucky across each of the categories of the individual variables. Logistic regression was used to estimate the effects of pharmacist demographic characteristics and experiences with gabapentin on their support of gabapentin reclassification as a CS.
RESULTS: One thousand seven hundred sixty-nine surveys were collected (response rate = 34.2%). Responding community pharmacists (n = 1084) believe that the abuse and diversion of gabapentin are a problem in their communities, with 9 in 10 (89.6%) indicating that they agree or strongly agree. More than three-fourths (87.5%) indicated support for reclassifying gabapentin as a CS. Common reasons for opposition to gabapentin regulatory changes were that they would not reduce or eliminate abuse (45.8%) and that they would be an inconvenience to patients (17.0%). Pharmacists practicing in independent pharmacies and pharmacists in practice greater than 20 years were less likely to indicate support for gabapentin reclassification.
CONCLUSION: Kentucky community pharmacists express considerable concern over the possible misuse and diversion of gabapentin and widely support regulatory changes reclassifying gabapentin as a CS.
Copyright © 2019 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2019        PMID: 30786971      PMCID: PMC9251728          DOI: 10.1016/j.japh.2018.12.018

Source DB:  PubMed          Journal:  J Am Pharm Assoc (2003)        ISSN: 1086-5802


  19 in total

1.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

2.  Gabapentin in neuropathic pain syndromes: a randomised, double-blind, placebo-controlled trial.

Authors:  M G Serpell
Journal:  Pain       Date:  2002-10       Impact factor: 6.961

3.  Treatment of alcohol withdrawal syndrome with gabapentin.

Authors:  U Bonnet; M Banger; F M Leweke; M Maschke; T Kowalski; M Gastpar
Journal:  Pharmacopsychiatry       Date:  1999-05       Impact factor: 5.788

4.  Prevalence of gabapentin in drug overdose postmortem toxicology testing results.

Authors:  Svetla Slavova; Alison Miller; Terry L Bunn; Jessica R White; David Kirschke; Tom Light; Daniel Christy; Gary Thompson; Ruth Winecker
Journal:  Drug Alcohol Depend       Date:  2018-03-10       Impact factor: 4.492

5.  Gabapentin treatment for alcohol dependence: a randomized clinical trial.

Authors:  Barbara J Mason; Susan Quello; Vivian Goodell; Farhad Shadan; Mark Kyle; Adnan Begovic
Journal:  JAMA Intern Med       Date:  2014-01       Impact factor: 21.873

Review 6.  A systematic review and meta-regression analysis of prophylactic gabapentin for postoperative pain.

Authors:  B Doleman; T P Heinink; D J Read; R J Faleiro; J N Lund; J P Williams
Journal:  Anaesthesia       Date:  2015-08-24       Impact factor: 6.955

7.  A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal.

Authors:  Hugh Myrick; Robert Malcolm; Patrick K Randall; Elizabeth Boyle; Raymond F Anton; Howard C Becker; Carrie L Randall
Journal:  Alcohol Clin Exp Res       Date:  2009-05-26       Impact factor: 3.455

Review 8.  Gabapentin: a new agent for the management of epilepsy.

Authors:  C O Andrews; J H Fischer
Journal:  Ann Pharmacother       Date:  1994-10       Impact factor: 3.154

9.  Use of gabapentin for perioperative pain control -- a meta-analysis.

Authors:  P W Peng; D N Wijeysundera; C Cf Li
Journal:  Pain Res Manag       Date:  2007       Impact factor: 3.037

Review 10.  Gabapentin's anti-nausea and anti-emetic effects: a review.

Authors:  Thomas Guttuso
Journal:  Exp Brain Res       Date:  2014-03-26       Impact factor: 1.972

View more
  1 in total

1.  Abuse-Deterrent Opioids: A Survey of Physician Beliefs, Behaviors, and Psychology.

Authors:  Nabarun Dasgupta; John R Brown; Maryalice Nocera; Allison Lazard; Svetla Slavova; Patricia R Freeman
Journal:  Pain Ther       Date:  2021-12-06
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.