| Literature DB >> 30786739 |
Jose A Diaz1, Prakash Saha2, Brian Cooley3, Olivia R Palmer1, Steven P Grover3, Nigel Mackman3, Thomas W Wakefield1, Peter K Henke1, Alberto Smith2, Brajesh K Lal4.
Abstract
Murine models are widely used valuable tools to study deep vein thrombosis. Leading experts in venous thrombosis research came together through the American Venous Forum to develop a consensus on maximizing the utility and application of available mouse models of venous thrombosis. In this work, we provide an algorithm for model selection, with discussion of the advantages, disadvantages, and applications of the main mouse models of venous thrombosis. Additionally, we provide a detailed surgical description of the models with guidelines to validate surgical technique.Entities:
Keywords: consensus; experimental animal models; surgical models; venous thromboembolism; venous thrombosis
Year: 2019 PMID: 30786739 DOI: 10.1161/ATVBAHA.118.311818
Source DB: PubMed Journal: Arterioscler Thromb Vasc Biol ISSN: 1079-5642 Impact factor: 8.311