Literature DB >> 30786733

Assessing evidence-based medicine and opioid/barbiturate as first-line acute treatment of pediatric migraine and primary headache: A retrospective observational study of health systems data.

Elizabeth K Seng1,2,3, Amy A Gelfand4, Robert A Nicholson5,6.   

Abstract

OBJECTIVES: To evaluate providers' use and predictors of evidence-based medicine or opioid/barbiturate as first-line acute treatment for children's initial presentation of acute migraine or primary headache.
METHODS: This retrospective, observational study utilized patient (children ages 6-17) and provider/encounter characteristics extracted from the patient's Electronic Health Record from 2008-2014 during an initial encounter for migraine or primary headache. The primary outcome was provider evidence-based medicine utilization; overall prescriptions and opioid/barbiturate prescriptions were also evaluated. Hierarchical linear modeling examined whether Level 1 (patient: Demographic, insurance type) and Level 2 (provider/encounter: Treatment setting/location, encounter diagnoses) characteristics influenced outcomes.
RESULTS: In all, 38,926 patients (56.7% female, mean age = 12.1) and 1617 providers were evaluated. Only 17.7% of patients were diagnosed with migraine; 16.1% received evidence-based medicine. Older children (OR = 1.07, p < 0.001), females (OR = 1.14, p < 0.001), and those diagnosed with migraine (OR = 4.71, p < 0.001) were more likely to receive evidence-based medicine. Among prescriptions, 15.8% were for opioids/barbiturates. Older children (OR = 1.14, p < 0.001) and those cared for in the emergency department/urgent care (OR = 2.02, p < 0.001) were at increased risk.
CONCLUSIONS: Demographics and migraine diagnosis are associated with evidence-based medicine and opioid/barbiturates. Primary care provides an opportunity to target provider interventions to enhance effective pediatric headache treatment.

Entities:  

Keywords:  Initial treatment; adherence to best practice; children and adolescents; emergency department; primary care; triptan

Year:  2019        PMID: 30786733      PMCID: PMC6933731          DOI: 10.1177/0333102419833080

Source DB:  PubMed          Journal:  Cephalalgia        ISSN: 0333-1024            Impact factor:   6.292


  33 in total

1.  Epidemiology of migraine among students from randomly selected secondary schools in Lodz.

Authors:  W Split; W Neuman
Journal:  Headache       Date:  1999 Jul-Aug       Impact factor: 5.887

Review 2.  Opioids should not be used in migraine.

Authors:  Stewart J Tepper
Journal:  Headache       Date:  2012-05       Impact factor: 5.887

3.  Efficacy of zolmitriptan nasal spray in adolescent migraine.

Authors:  Donald W Lewis; Paul Winner; Andrew D Hershey; Warren W Wasiewski
Journal:  Pediatrics       Date:  2007-08       Impact factor: 7.124

4.  Opioid tolerance development: a pharmacokinetic/pharmacodynamic perspective.

Authors:  Emily O Dumas; Gary M Pollack
Journal:  AAPS J       Date:  2008-11-07       Impact factor: 4.009

Review 5.  The treatment of pediatric migraine.

Authors:  Donald W Lewis; Marcy Yonker; Paul Winner; Michael Sowell
Journal:  Pediatr Ann       Date:  2005-06       Impact factor: 1.132

Review 6.  Risk of drug dependence and abuse posed by barbiturate-containing analgesics.

Authors:  E M Sellers; K Hoornweg; U E Busto; M K Romach
Journal:  Can J Clin Pharmacol       Date:  1999

7.  Prevalence and diagnosis of migraine in patients consulting their physician with a complaint of headache: data from the Landmark Study.

Authors:  Stewart J Tepper; Carl G H Dahlöf; Andrew Dowson; Lawrence Newman; Hank Mansbach; Martin Jones; Ba Pham; Chris Webster; Reijo Salonen
Journal:  Headache       Date:  2004-10       Impact factor: 5.887

8.  Quality of life in paediatric migraine: characterization of age-related effects using PedsQL 4.0.

Authors:  S W Powers; S R Patton; K A Hommel; A D Hershey
Journal:  Cephalalgia       Date:  2004-02       Impact factor: 6.292

9.  Efficacy and tolerability of almotriptan in adolescents: a randomized, double-blind, placebo-controlled trial.

Authors:  Steven L Linder; Ninan T Mathew; Roger K Cady; Gary Finlayson; Gary Ishkanian; Donald W Lewis
Journal:  Headache       Date:  2008-05-14       Impact factor: 5.887

10.  Randomized trial of sumatriptan and naproxen sodium combination in adolescent migraine.

Authors:  Frederick J Derosier; Donald Lewis; Andrew D Hershey; Paul K Winner; Eric Pearlman; Arnold David Rothner; Steven L Linder; David K Goodman; Theresa B Jimenez; Wendy K Granberry; M Chris Runken
Journal:  Pediatrics       Date:  2012-05-14       Impact factor: 7.124

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  2 in total

Review 1.  Factors Associated With, and Mitigation Strategies for, Health Care Disparities Faced by Patients With Headache Disorders.

Authors:  Jessica Kiarashi; Juliana VanderPluym; Christina L Szperka; Scott Turner; Mia T Minen; Susan Broner; Alexandra C Ross; Amanda E Wagstaff; Marissa Anto; Maya Marzouk; Teshamae S Monteith; Noah Rosen; Salvador L Manrriquez; Elizabeth Seng; Alan Finkel; Larry Charleston
Journal:  Neurology       Date:  2021-06-09       Impact factor: 11.800

Review 2.  Headache in Children and Adolescents.

Authors:  Christina Szperka
Journal:  Continuum (Minneap Minn)       Date:  2021-06-01
  2 in total

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