Thomas F Lüscher1,2,3, Allan Davies4. 1. Professor of Cardiology, Director of Research, Education & Development, Royal Brompton and Harefield Hospitals, Imperial College, Sydney Street, London, UK. 2. Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland. 3. EHJ Editorial Office, Zurich Heart House, Hottingerstreet 14, Zurich, Switzerland. 4. Royal Brompton and Harefield Hospitals, Imperial College, Sydney Street, London, London, UK.