Literature DB >> 30782814

Blockade of RAF and autophagy is the one-two punch to take out Ras.

Eileen White1,2.   

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Year:  2019        PMID： 30782814      PMCID： PMC6410840          DOI： 10.1073/pnas.1900800116

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  21 in total

1.  Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.

Authors:  Annan Yang; Grit Herter-Sprie; Haikuo Zhang; Elaine Y Lin; Douglas Biancur; Xiaoxu Wang; Jiehui Deng; Josephine Hai; Shenghong Yang; Kwok-Kin Wong; Alec C Kimmelman
Journal:  Cancer Discov       Date:  2018-01-09       Impact factor: 39.397

Review 2.  A model for RAS mutation patterns in cancers: finding the sweet spot.

Authors:  Siqi Li; Allan Balmain; Christopher M Counter
Journal:  Nat Rev Cancer       Date:  2018-12       Impact factor: 60.716

Review 3.  Targeting autophagy in cancer.

Authors:  Angelique V Onorati; Matheus Dyczynski; Rani Ojha; Ravi K Amaravadi
Journal:  Cancer       Date:  2018-04-19       Impact factor: 6.860

4.  Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis.

Authors:  Jessie Yanxiang Guo; Gizem Karsli-Uzunbas; Robin Mathew; Seena C Aisner; Jurre J Kamphorst; Anne M Strohecker; Guanghua Chen; Sandy Price; Wenyun Lu; Xin Teng; Eric Snyder; Urmila Santanam; Robert S Dipaola; Tyler Jacks; Joshua D Rabinowitz; Eileen White
Journal:  Genes Dev       Date:  2013-07-01       Impact factor: 11.361

Review 5.  Autophagy and Tumor Metabolism.

Authors:  Alec C Kimmelman; Eileen White
Journal:  Cell Metab       Date:  2017-05-02       Impact factor: 27.287

6.  Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors.

Authors:  Jean M Mulcahy Levy; Joshua C Thompson; Andrea M Griesinger; Vladimir Amani; Andrew M Donson; Diane K Birks; Michael J Morgan; David M Mirsky; Michael H Handler; Nicholas K Foreman; Andrew Thorburn
Journal:  Cancer Discov       Date:  2014-05-13       Impact factor: 39.397

7.  Autophagy maintains tumour growth through circulating arginine.

Authors:  Laura Poillet-Perez; Xiaoqi Xie; Le Zhan; Yang Yang; Daniel W Sharp; Zhixian Sherrie Hu; Xiaoyang Su; Anurag Maganti; Cherry Jiang; Wenyun Lu; Haiyan Zheng; Marcus W Bosenberg; Janice M Mehnert; Jessie Yanxiang Guo; Edmund Lattime; Joshua D Rabinowitz; Eileen White
Journal:  Nature       Date:  2018-11-14       Impact factor: 49.962

8.  Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis.

Authors:  Vrushank Bhatt; Khoosheh Khayati; Zhixian Sherrie Hu; Amy Lee; Wali Kamran; Xiaoyang Su; Jessie Yanxiang Guo
Journal:  Genes Dev       Date:  2019-01-28       Impact factor: 11.361

9.  p53 status determines the role of autophagy in pancreatic tumour development.

Authors:  Mathias T Rosenfeldt; Jim O'Prey; Jennifer P Morton; Colin Nixon; Gillian MacKay; Agata Mrowinska; Amy Au; Taranjit Singh Rai; Liang Zheng; Rachel Ridgway; Peter D Adams; Kurt I Anderson; Eyal Gottlieb; Owen J Sansom; Kevin M Ryan
Journal:  Nature       Date:  2013-12-04       Impact factor: 49.962

10.  Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells.

Authors:  Jessie Yanxiang Guo; Xin Teng; Saurabh V Laddha; Sirui Ma; Stephen C Van Nostrand; Yang Yang; Sinan Khor; Chang S Chan; Joshua D Rabinowitz; Eileen White
Journal:  Genes Dev       Date:  2016-08-11       Impact factor: 11.361
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  4 in total

Review 1.  The role of metabolic ecosystem in cancer progression - metabolic plasticity and mTOR hyperactivity in tumor tissues.

Authors:  Anna Sebestyén; Titanilla Dankó; Dániel Sztankovics; Dorottya Moldvai; Regina Raffay; Catherine Cervi; Ildikó Krencz; Viktória Zsiros; András Jeney; Gábor Petővári
Journal:  Cancer Metastasis Rev       Date:  2022-01-14       Impact factor: 9.264

Review 2.  Role of tumor and host autophagy in cancer metabolism.

Authors:  Laura Poillet-Perez; Eileen White
Journal:  Genes Dev       Date:  2019-06-01       Impact factor: 11.361

Review 3.  Autophagy Regulates Stress Responses, Metabolism, and Anticancer Immunity.

Authors:  Eileen White; Edmund C Lattime; Jessie Yanxiang Guo
Journal:  Trends Cancer       Date:  2021-06-07

Review 4.  Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment.

Authors:  Samuel A Kerk; Thales Papagiannakopoulos; Yatrik M Shah; Costas A Lyssiotis
Journal:  Nat Rev Cancer       Date:  2021-07-09       Impact factor: 69.800
  4 in total

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